PMID- 8313502
OWN - NLM
STAT- MEDLINE
DCOM- 19940322
LR  - 20190512
IS  - 0143-3334 (Print)
IS  - 0143-3334 (Linking)
VI  - 15
IP  - 2
DP  - 1994 Feb
TI  - Caloric restriction profoundly inhibits liver tumor formation after initiation by 
      6-nitrochrysene in male mice.
PG  - 159-61
AB  - Caloric restriction (CR) inhibited strongly the incidence of chemically-induced 
      tumors in the neonatal B6C3F1 mouse tumorigenicity bioassay, when begun 3 months 
      after treatment with the potent carcinogen 6-nitrochrysene. These data indicate 
      that CR can have a profound inhibitory effect on tumor development even long 
      after metabolic activation and DNA repair have occurred.
FAU - Fu, P P
AU  - Fu PP
AD  - National Center for Toxicological Research, Jefferson, AR 72079.
FAU - Dooley, K L
AU  - Dooley KL
FAU - Von Tungeln, L S
AU  - Von Tungeln LS
FAU - Bucci, T
AU  - Bucci T
FAU - Hart, R W
AU  - Hart RW
FAU - Kadlubar, F F
AU  - Kadlubar FF
LA  - eng
PT  - Journal Article
PL  - England
TA  - Carcinogenesis
JT  - Carcinogenesis
JID - 8008055
RN  - 0 (Carcinogens)
RN  - 0 (Chrysenes)
RN  - 82ZK83O33Y (6-nitrochrysene)
SB  - IM
MH  - Adenoma/chemically induced/*prevention & control
MH  - Animals
MH  - Biotransformation
MH  - *Carcinogens/pharmacokinetics
MH  - *Chrysenes/pharmacokinetics
MH  - DNA Damage
MH  - *Energy Intake
MH  - Food Deprivation
MH  - Liver Neoplasms, Experimental/chemically induced/*prevention & control
MH  - Male
MH  - Mice
EDAT- 1994/02/01 00:00
MHDA- 1994/02/01 00:01
CRDT- 1994/02/01 00:00
PHST- 1994/02/01 00:00 [pubmed]
PHST- 1994/02/01 00:01 [medline]
PHST- 1994/02/01 00:00 [entrez]
AID - 10.1093/carcin/15.2.159 [doi]
PST - ppublish
SO  - Carcinogenesis. 1994 Feb;15(2):159-61. doi: 10.1093/carcin/15.2.159.