PMID- 8319381
OWN - NLM
STAT- MEDLINE
DCOM- 19930803
LR  - 20111117
IS  - 0009-918X (Print)
IS  - 0009-918X (Linking)
VI  - 33
IP  - 2
DP  - 1993 Feb
TI  - [Clinical and pathological study of myelopathy accompanied with cervical spinal 
      canal stenosis--with special reference to complication of mental retardation or 
      cerebral palsy].
PG  - 121-9
AB  - We studied 3 cases with myelopathy caused by cervical spinal canal stenosis 
      (developmental), who had been suffering from walking difficulty followed by 
      tetraplegia, clinically and pathologically. In all 3 cases, mental retardation 
      and/or cerebral palsy was diagnosed. We hypothesized that the brain damage in the 
      developmental stage might also cause developmental disturbance in the cervical 
      spine. In all cases, pathological investigation showed decreased antero-posterior 
      diameter and degeneration in the gray matter and in the lateral and posterior 
      column in the involved cervical spinal cord. The findings, such as relative 
      preservation of the anterior column and cyst formation in the gray matter, were 
      thought to be in common with cervical spondylotic myelopathy or ossification of 
      the occipital longitudinal ligament (OPLL) which had been reported before. In one 
      case we found aberrant peripheral nerve bundles and peripheral type remyelination 
      in the transverse spinal cord lesion. Compared to the pathological change in the 
      OPLL, our cases showed more severe degenerative change in the spinal segments 
      with a relatively preserved antero-posterior diameter of the spinal cord, which 
      supports the theory that the dynamic factor plays a more important role than the 
      static compression factor. We concluded that the aging process and/or dystonic 
      neck movement added spondylotic change to the narrow canal, and excess movement 
      of the neck and/or falls caused dynamic injury to the spinal cord and secondary 
      circulatory disturbance further worsened spinal lesions. When elderly patients 
      with cerebral palsy develop motor symptoms, we should consider cervical spinal 
      stenosis as a possible cause.
FAU - Nokura, K
AU  - Nokura K
AD  - Department of Internal Medicine, Nagoya-shi Koseiin Geriatric Hospital, Japan.
FAU - Hashizume, Y
AU  - Hashizume Y
FAU - Inagaki, T
AU  - Inagaki T
FAU - Ojika, K
AU  - Ojika K
FAU - Yamamoto, M
AU  - Yamamoto M
LA  - jpn
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Japan
TA  - Rinsho Shinkeigaku
JT  - Rinsho shinkeigaku = Clinical neurology
JID - 0417466
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Cerebral Palsy/complications
MH  - Cervical Vertebrae
MH  - Female
MH  - Humans
MH  - Intellectual Disability/complications
MH  - Male
MH  - Spinal Cord/pathology
MH  - Spinal Cord Diseases/*etiology/pathology/physiopathology
MH  - Spinal Stenosis/*complications
EDAT- 1993/02/01 00:00
MHDA- 1993/02/01 00:01
CRDT- 1993/02/01 00:00
PHST- 1993/02/01 00:00 [pubmed]
PHST- 1993/02/01 00:01 [medline]
PHST- 1993/02/01 00:00 [entrez]
PST - ppublish
SO  - Rinsho Shinkeigaku. 1993 Feb;33(2):121-9.