PMID- 8321543
OWN - NLM
STAT- MEDLINE
DCOM- 19930730
LR  - 20211203
IS  - 0301-1569 (Print)
IS  - 0301-1569 (Linking)
VI  - 55
IP  - 3
DP  - 1993 May-Jun
TI  - Human leukocyte antigens in patients with inner ear diseases of unknown etiology.
PG  - 125-34
AB  - The immune response genes that control the immune response and recognition of 
      'self' from 'nonself' are closely linked with the human leukocyte antigen (HLA) 
      complex. Sixty-six HLA antigens were typed in 42 Caucasian patients with inner 
      ear diseases of unknown etiology. All of these patients had positive serum 
      antibodies against the inner ear structures as detected by an indirect 
      immunofluorescence assay. Results revealed that none of the 66 HLA antigens was 
      associated with the inner ear diseases. Reviewing results from other studies on 
      HLA association in inner ear diseases shows that the findings are inconsistent 
      with each other. The conclusion that HLA associations occur with inner ear 
      diseases cannot be reached.
FAU - Xu, L
AU  - Xu L
AD  - Department of Otorhinolaryngology, University Hospital, Basel, Switzerland.
FAU - Pfaltz, C R
AU  - Pfaltz CR
FAU - Arnold, W
AU  - Arnold W
LA  - eng
PT  - Journal Article
PL  - Switzerland
TA  - ORL J Otorhinolaryngol Relat Spec
JT  - ORL; journal for oto-rhino-laryngology and its related specialties
JID - 0334721
RN  - 0 (Antibodies)
RN  - 0 (HLA Antigens)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Antibodies/blood
MH  - Autoimmune Diseases/complications/physiopathology
MH  - Chromosomes, Human, Pair 6/immunology
MH  - Ear Diseases/diagnosis/immunology/*physiopathology
MH  - Ear, Inner/immunology/*physiopathology
MH  - Female
MH  - Fluorescent Antibody Technique
MH  - HLA Antigens/genetics/immunology
MH  - Haplotypes
MH  - Hearing Loss, Sensorineural/etiology/immunology/physiopathology
MH  - Humans
MH  - Immunosuppression Therapy
MH  - Male
MH  - Middle Aged
MH  - Spondylitis, Ankylosing/etiology/immunology/physiopathology
EDAT- 1993/05/01 00:00
MHDA- 1993/05/01 00:01
CRDT- 1993/05/01 00:00
PHST- 1993/05/01 00:00 [pubmed]
PHST- 1993/05/01 00:01 [medline]
PHST- 1993/05/01 00:00 [entrez]
AID - 10.1159/000276403 [doi]
PST - ppublish
SO  - ORL J Otorhinolaryngol Relat Spec. 1993 May-Jun;55(3):125-34. doi: 
      10.1159/000276403.