PMID- 8324302 OWN - NLM STAT- MEDLINE DCOM- 19930812 LR - 20190914 IS - 1053-1807 (Print) IS - 1053-1807 (Linking) VI - 3 IP - 3 DP - 1993 May-Jun TI - MR characterization of blood flow in native and grafted internal mammary arteries. PG - 443-50 AB - In the postoperative patient with anginal symptoms, differentiation between bypass graft compromise and nonischemic causes has until now been accomplished only by means of x-ray angiography. A non-invasive test is clearly desirable. The authors used a cine phase-contrast (PC) magnetic resonance (MR) imaging technique to characterize blood flow in native and grafted internal mammary arteries (IMAs). Ten volunteers and 15 patients who had recently undergone IMA coronary artery bypass grafting were imaged. Cine PC MR imaging was performed in the transaxial plane at the level of the pulmonary artery bifurcation. Flow in both IMAs was quantified and expressed as a percentage of cardiac output measured in the ascending aorta. In the 15 patients, flow analysis was performed in both the native and grafted IMAs. In the volunteers, IMA blood flow ranged from 2.1% to 4.3% of cardiac output on the left (mean, 3.5%) and 2.1% to 5.1% (mean, 3.5%) on the right. There was considerable intersubject variability, with coefficients of variation of 10.7% for the left and 12.3% for the right IMA. Intrasubject variability was limited, with estimated common standard deviations of 0.45% of cardiac output (range, 0.2%-1.1%) for the left and 0.39% (range, 0.1%-0.6%) for the right IMA. Flow in grafted IMAs was identified in 13 of 15 patients. In one of two patients without demonstrable IMA graft flow, cardiac catheterization confirmed lack of flow. IMA graft flow varied from 28 to 164 mL/min (mean, 80.3 mL/min). This study shows the feasibility of using cine PC MR imaging as a quantitative method of evaluating blood flow in IMA coronary artery bypass grafts. FAU - Debatin, J F AU - Debatin JF AD - Department of Radiology, Stanford University Medical Center, CA 94305. FAU - Strong, J A AU - Strong JA FAU - Sostman, H D AU - Sostman HD FAU - Negro-Vilar, R AU - Negro-Vilar R FAU - Paine, S S AU - Paine SS FAU - Douglas, J M Jr AU - Douglas JM Jr FAU - Pelc, N J AU - Pelc NJ LA - eng PT - Journal Article PL - United States TA - J Magn Reson Imaging JT - Journal of magnetic resonance imaging : JMRI JID - 9105850 SB - IM MH - Adult MH - Aged MH - *Blood Flow Velocity MH - *Coronary Artery Bypass MH - Female MH - Humans MH - *Magnetic Resonance Imaging MH - Male MH - Mammary Arteries/*physiopathology/transplantation MH - Middle Aged EDAT- 1993/05/01 00:00 MHDA- 2001/03/28 10:01 CRDT- 1993/05/01 00:00 PHST- 1993/05/01 00:00 [pubmed] PHST- 2001/03/28 10:01 [medline] PHST- 1993/05/01 00:00 [entrez] AID - 10.1002/jmri.1880030303 [doi] PST - ppublish SO - J Magn Reson Imaging. 1993 May-Jun;3(3):443-50. doi: 10.1002/jmri.1880030303.