PMID- 8328459
OWN - NLM
STAT- MEDLINE
DCOM- 19930809
LR  - 20200824
IS  - 0002-9297 (Print)
IS  - 1537-6605 (Electronic)
IS  - 0002-9297 (Linking)
VI  - 53
IP  - 2
DP  - 1993 Aug
TI  - Characterization of supernumerary ring marker chromosomes by fluorescence in situ 
      hybridization (FISH).
PG  - 433-42
AB  - Five cases with small supernumerary ring chromosomes are characterized at the 
      molecular level. Routine chromosome banding analysis was insufficient for 
      identification of the ring chromosomes, and none of them was DA/DAPI positive. 
      Fluorescence in situ hybridization utilizing repetitive centromeric probes for 
      all chromosomes has determined that one of these five ring chromosomes originates 
      in each of chromosomes 4, 7, 8, 9, and 20. Chromosome painting with 
      chromosome-specific libraries has confirmed this and excluded the involvement of 
      additional chromosomes in the rearrangements.
FAU - Blennow, E
AU  - Blennow E
AD  - Department of Clinical Genetics, Karolinska Hospital, Stockholm, Sweden.
FAU - Anneren, G
AU  - Anneren G
FAU - Bui, T H
AU  - Bui TH
FAU - Berggren, E
AU  - Berggren E
FAU - Asadi, E
AU  - Asadi E
FAU - Nordenskjold, M
AU  - Nordenskjold M
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Am J Hum Genet
JT  - American journal of human genetics
JID - 0370475
RN  - 0 (Genetic Markers)
SB  - IM
MH  - Abnormalities, Multiple/*genetics
MH  - Adult
MH  - Child, Preschool
MH  - Chromosome Aberrations/*diagnosis/*genetics
MH  - Chromosome Disorders
MH  - Chromosomes, Human, Pair 20
MH  - Chromosomes, Human, Pair 4
MH  - Chromosomes, Human, Pair 7
MH  - Chromosomes, Human, Pair 8
MH  - Chromosomes, Human, Pair 9
MH  - Female
MH  - *Genetic Markers
MH  - Holoprosencephaly/genetics
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Infant
MH  - Male
MH  - *Ring Chromosomes
PMC - PMC1682354
EDAT- 1993/08/01 00:00
MHDA- 1993/08/01 00:01
PMCR- 1994/02/01
CRDT- 1993/08/01 00:00
PHST- 1993/08/01 00:00 [pubmed]
PHST- 1993/08/01 00:01 [medline]
PHST- 1993/08/01 00:00 [entrez]
PHST- 1994/02/01 00:00 [pmc-release]
PST - ppublish
SO  - Am J Hum Genet. 1993 Aug;53(2):433-42.