PMID- 8331819 OWN - NLM STAT- MEDLINE DCOM- 19930817 LR - 20190830 IS - 0300-9173 (Print) IS - 0300-9173 (Linking) VI - 30 IP - 3 DP - 1993 Mar TI - [Endocrine hypertension]. PG - 182-7 AB - Endocrine Hypertension, is, in a narrow sense, defined as adrenal hypertension, including mainly pheochromocytoma, Cushing's syndrome, a syndrome of primary aldosteronism and it's related mineralocorticoid excess disorders. In memory of a great contribution to hypertensiology by the late Prof. Murakami, who was the first author to write on pheochromocytoma in Japan, this paper is dedicated to reviewing the current status of adrenal hypertension in Japan from the epidemiological viewpoint, putting emphasis upon the clinical characteristics of aged patients with adrenal hypertension. Secondly, some topics in the research field of each adrenal hypertension are briefly introduced. Thirdly, our recent data are presented, showing 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD) mRNA expression in resistance vessels and decreased 11 beta-HSD activities in vessels in SHR which supports the hypothesis that there might exist a subtype identified as partial impairment of 11 beta-HSD in patients with essential hypertension. FAU - Takeda, R AU - Takeda R AD - Second Department of Internal Medicine, School of Medicine, Kanazawa University. LA - jpn PT - English Abstract PT - Journal Article PT - Review PL - Japan TA - Nihon Ronen Igakkai Zasshi JT - Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics JID - 7507332 RN - EC 1.1.- (17-Hydroxysteroid Dehydrogenases) SB - IM MH - 17-Hydroxysteroid Dehydrogenases/*deficiency MH - Adrenal Gland Neoplasms/*complications MH - Aged MH - Animals MH - Cushing Syndrome/*complications MH - Humans MH - Hyperaldosteronism/*complications MH - Hypertension/classification/epidemiology/*etiology MH - Japan/epidemiology MH - Male MH - Middle Aged MH - Pheochromocytoma/*complications MH - Rats RF - 14 EDAT- 1993/03/01 00:00 MHDA- 1993/03/01 00:01 CRDT- 1993/03/01 00:00 PHST- 1993/03/01 00:00 [pubmed] PHST- 1993/03/01 00:01 [medline] PHST- 1993/03/01 00:00 [entrez] AID - 10.3143/geriatrics.30.182 [doi] PST - ppublish SO - Nihon Ronen Igakkai Zasshi. 1993 Mar;30(3):182-7. doi: 10.3143/geriatrics.30.182.