PMID- 8336318 OWN - NLM STAT- MEDLINE DCOM- 19930826 LR - 20051117 IS - 0315-162X (Print) IS - 0315-162X (Linking) VI - 20 IP - 5 DP - 1993 May TI - Lambda light chain deposition disease presenting as an amyloid-like arthropathy. PG - 880-4 AB - We describe a case of lambda light chain deposition disease (LCDD) which presented with symmetric, seronegative, nonerosive arthritis associated with skin nodules and widespread, progressive soft tissue induration. Multiple biopsies disclosed Congo red nonbirefringent deposits which stained strongly with lambda light chain antiserum, allowing distinction from amyloid arthropathy. This is the first report of musculoskeletal involvement in LCDD. FAU - Rivest, C AU - Rivest C AD - Division of Rheumatology, Hopital Notre-Dame, University of Montreal School of Medicine, PQ, Canada. FAU - Turgeon, P P AU - Turgeon PP FAU - Senecal, J L AU - Senecal JL LA - eng PT - Case Reports PT - Journal Article PL - Canada TA - J Rheumatol JT - The Journal of rheumatology JID - 7501984 RN - 0 (Immunoglobulin Light Chains) RN - 0 (Immunoglobulin lambda-Chains) SB - IM MH - Adult MH - Amyloidosis/*diagnosis MH - Diagnosis, Differential MH - Humans MH - Immunoglobulin Light Chains/*metabolism MH - Immunoglobulin lambda-Chains/*metabolism MH - Joint Diseases/*diagnosis MH - Male MH - Muscles/pathology MH - Paraproteinemias/*diagnosis/pathology EDAT- 1993/05/01 00:00 MHDA- 1993/05/01 00:01 CRDT- 1993/05/01 00:00 PHST- 1993/05/01 00:00 [pubmed] PHST- 1993/05/01 00:01 [medline] PHST- 1993/05/01 00:00 [entrez] PST - ppublish SO - J Rheumatol. 1993 May;20(5):880-4.