PMID- 8341854 OWN - NLM STAT- MEDLINE DCOM- 19930902 LR - 20180216 IS - 0025-7931 (Print) IS - 0025-7931 (Linking) VI - 60 IP - 2 DP - 1993 TI - Diffuse interstitial fibrosis in nonasbestos pneumoconiosis--a pathological study. PG - 120-6 AB - Pathological examinations of 233 consecutive autopsy cases with nonasbestos pneumonconiosis revealed evidence of diffuse interstitial fibrosis (DIF) in 64 (27.5%), among whom 45 (19.3%) showed bilateral involvement and 9 (3.9%) extensive disease closely resembling usual interstitial pneumonia. The patients with DIF were significantly older and had longer occupational histories as compared with those without DIF. There was no correlation between the occurrence of DIF and the type of the underlying disease (silicosis or mixed dust pneumoconiosis) except that an extensive DIF was more frequently associated with mixed dust pneumoconiosis. The extensive DIF developed an in situ malignancy much more frequently (33.3%) than the focal disease (2.6%). FAU - Honma, K AU - Honma K AD - Department of Pathology, Dokkyo University School of Medicine Mibu, Tochigi, Japan. FAU - Chiyotani, K AU - Chiyotani K LA - eng PT - Journal Article PL - Switzerland TA - Respiration JT - Respiration; international review of thoracic diseases JID - 0137356 SB - IM MH - Age Factors MH - Aged MH - Female MH - Humans MH - Lung/*pathology MH - Male MH - Occupations MH - Pneumoconiosis/*pathology MH - Pulmonary Fibrosis/*pathology MH - Silicosis/*pathology MH - Time Factors EDAT- 1993/01/01 00:00 MHDA- 1993/01/01 00:01 CRDT- 1993/01/01 00:00 PHST- 1993/01/01 00:00 [pubmed] PHST- 1993/01/01 00:01 [medline] PHST- 1993/01/01 00:00 [entrez] AID - 10.1159/000196185 [doi] PST - ppublish SO - Respiration. 1993;60(2):120-6. doi: 10.1159/000196185.