PMID- 8348593
OWN - NLM
STAT- MEDLINE
DCOM- 19930916
LR  - 20190830
IS  - 0098-6569 (Print)
IS  - 0098-6569 (Linking)
VI  - 29
IP  - 2
DP  - 1993 Jun
TI  - Management of typical and dysplastic pulmonic stenosis, uncomplicated or 
      associated with complex intracardiac defects, in juveniles and adults: use of 
      percutaneous balloon pulmonary valvuloplasty with eight-month hemodynamic 
      follow-up.
PG  - 105-12
AB  - To alleviate large fixed right ventricular (RV) outflow gradients, percutaneous 
      balloon dilatation of pulmonic stenosis (PS) was performed in 38 patients with 
      mean age of 14 +/- 14 years (median: 9 years, age range: 9 months to 63 years). 
      There were 21 males and 17 females. Thirty-four patients had typical PS (5 of 
      them also having other complex congenital cardiac anomalies, while 13 additional 
      patients had a patent foramen ovale); 2 further subjects had subpulmonic, and 2 
      dysplastic pulmonary valvular obstructions. Sixteen patients were in the New York 
      Heart Association (NYHA) Class I, 15 in Class II, 6 in Class III, and 1 in Class 
      IV. Electrocardiographic (ECG) evidence of right ventricular hypertrophy (RVH) 
      was present in 29 patients (76%); 3 patients had right bundle branch block 
      (RBBB). For the entire group, there was a marked decrease in the mean systolic 
      transpulmonic gradient in the immediate post-valvuloplasty period (from 97 +/- 43 
      to 26 +/- 17 mmHg; P < 0.0001). One patient expired 8 hours post-valvuloplasty 
      (he was in the NYHA Class IV, and had severe RV failure). No other cardiovascular 
      complications were encountered; the median hospital stay was 3 days (range: 1-10 
      days). At an 8-month follow-up, 12 patients who were reevaluated invasively had a 
      median transpulmonic gradient of 27 mmHg (range: 5-92 mmHg) as compared to their 
      pre-valvuloplasty values of 84 mmHg (range: 49-142 mmHg; P < 0.004).(ABSTRACT 
      TRUNCATED AT 250 WORDS)
FAU - David, S W
AU  - David SW
AD  - Department of Internal Medicine, Providence Hospital, Southfield, Michigan.
FAU - Goussous, Y M
AU  - Goussous YM
FAU - Harbi, N
AU  - Harbi N
FAU - Doghmi, F
AU  - Doghmi F
FAU - Hiari, A
AU  - Hiari A
FAU - Krayyem, M
AU  - Krayyem M
FAU - Ferlinz, J
AU  - Ferlinz J
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Cathet Cardiovasc Diagn
JT  - Catheterization and cardiovascular diagnosis
JID - 7508512
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Catheterization/*instrumentation
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Defects, Congenital/physiopathology/*therapy
MH  - Heart Failure/physiopathology/therapy
MH  - Hemodynamics/*physiology
MH  - Humans
MH  - Infant
MH  - Male
MH  - Middle Aged
MH  - Pulmonary Valve/abnormalities/physiopathology
MH  - Pulmonary Valve Stenosis/congenital/physiopathology/*therapy
MH  - Pulmonary Wedge Pressure/physiology
MH  - Systole/physiology
EDAT- 1993/06/01 00:00
MHDA- 1993/06/01 00:01
CRDT- 1993/06/01 00:00
PHST- 1993/06/01 00:00 [pubmed]
PHST- 1993/06/01 00:01 [medline]
PHST- 1993/06/01 00:00 [entrez]
AID - 10.1002/ccd.1810290204 [doi]
PST - ppublish
SO  - Cathet Cardiovasc Diagn. 1993 Jun;29(2):105-12. doi: 10.1002/ccd.1810290204.