PMID- 8365742
OWN - NLM
STAT- MEDLINE
DCOM- 19931007
LR  - 20220318
IS  - 0019-4832 (Print)
IS  - 0019-4832 (Linking)
VI  - 45
IP  - 1
DP  - 1993 Jan-Feb
TI  - A clinico-hematological study of iron deficiency anemia and its correlation with 
      hyperviscosity symptoms in cyanotic congenital heart disease.
PG  - 53-5
AB  - The present study was carried out in 33 cases of cyanotic congenital heart 
      disease (CCHD) to determine the prevalence of iron deficiency anemia (IDA) and 
      its correlation to hyperviscosity symptoms in terms of hematocrit levels. 
      Furthermore, the study was aimed at assessing the response to low dose iron 
      therapy (60 mg of elemental iron once daily) in relieving symptoms of 
      hyperviscosity. All these cases were evaluated for presence of symptoms of 
      hyperviscosity and later subjected to various hematological & biochemical 
      parameters of iron deficiency anemia including hemoglobin (Hb), pack cell volume 
      (PCV), mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration 
      (MCHC), serum iron, total iron binding capacity respectively. Results showed 
      presence of IDA in 6/33 cases (18.2%) and hyperviscosity symptoms in 10/33 cases 
      (30.3%). Amongst the group with symptoms of hyperviscosity, in the subset having 
      IDA these symptoms were observed at PCV levels of 0.52 L/L to 0.58 L/L in 
      contrast to the subset not deficient in iron where the symptoms occurred at a PCV 
      0.68 L/L. Relief of symptoms of hyperviscosity was evident with a minimal rise of 
      mean hemoglobin by 2.1 gm/dl. It was concluded that IDA was not an uncommon 
      finding in CCHD cases and that it leads to symptoms of hyperviscosity at a level 
      of PCV much lower than those known to produce these symptoms. Finally low dose 
      iron therapy was found effective in relieving the symptoms of hyperviscosity.
FAU - Gaiha, M
AU  - Gaiha M
AD  - Department of Medicine & Cardiology, Maulana Azad Medical College, LNJPN 
      Hospital, New Delhi.
FAU - Sethi, H P
AU  - Sethi HP
FAU - Sudha, R
AU  - Sudha R
FAU - Arora, R
AU  - Arora R
FAU - Acharya, N R
AU  - Acharya NR
LA  - eng
PT  - Journal Article
PL  - India
TA  - Indian Heart J
JT  - Indian heart journal
JID - 0374675
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Anemia, Hypochromic/*blood/complications
MH  - Blood Viscosity/*physiology
MH  - Cyanosis
MH  - Female
MH  - Heart Defects, Congenital/*blood/complications
MH  - Humans
MH  - Male
EDAT- 1993/01/01 00:00
MHDA- 1993/01/01 00:01
CRDT- 1993/01/01 00:00
PHST- 1993/01/01 00:00 [pubmed]
PHST- 1993/01/01 00:01 [medline]
PHST- 1993/01/01 00:00 [entrez]
PST - ppublish
SO  - Indian Heart J. 1993 Jan-Feb;45(1):53-5.