PMID- 8373106
OWN - NLM
STAT- MEDLINE
DCOM- 19931008
LR  - 20200825
IS  - 0304-4602 (Print)
IS  - 0304-4602 (Linking)
VI  - 22
IP  - 3
DP  - 1993 May
TI  - Fasting blood sugar level: a determinant for in-hospital outcome in patients with 
      first myocardial infarction and without glucose intolerance.
PG  - 291-5
AB  - The body responds to stress, e.g. during infections or acute illnesses, by a 
      variety of neurohormonal mechanisms. Some of these physiological responses 
      sometimes lead to an elevation of the blood sugar level (BSL). BSL is a 
      biochemical parameter which is readily and rapidly assayed. The aim of our study 
      was to determine whether the glycaemic state of patients with their first 
      myocardial infarction and without previous glucose intolerance was of predictive 
      value for the type of outcome during the in-hospital and post-hospitalisation 
      periods. We also delineated the factors which determined subsequent glucose 
      tolerance in this group of patients. Forty-four consecutive patients were studied 
      and those with complicated in-hospital outcome had a significantly higher mean 
      BSL at admission (ABSL) and fasting BSL (FBSL). FBSL was shown to be a predictor 
      for in-hospital outcome. The odds ratio for a complicated in-hospital outcome was 
      3.3 times for patients with a FBSL of greater than 6.7 mmol/l (120 mg/dl) than 
      those without (p = 0.0175). We could not identify a predictor for an adverse 
      outcome in the post-hospitalisation period. Oral glucose tolerance test was 
      performed on twenty-seven patients at least six weeks after the infarction. 
      Twelve were normal and fifteen were abnormal (six were diabetic and nine had 
      impaired glucose tolerance). The odds ratio for patients with glycosylated 
      haemoglobin level (HbAlc) between 7.5 and 9.5% was 2.19 higher than those less 
      than 7.5% (p = 0.049). In conclusion, the FBSL is a determinant for the outcome 
      for these patients during the in-hospital and not the post-hospitalisation 
      period.(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Mak, K H
AU  - Mak KH
AD  - Department of Medicine, Alexandra Hospital.
FAU - Mah, P K
AU  - Mah PK
FAU - Tey, B H
AU  - Tey BH
FAU - Sin, F L
AU  - Sin FL
FAU - Chia, G
AU  - Chia G
LA  - eng
PT  - Journal Article
PL  - Singapore
TA  - Ann Acad Med Singap
JT  - Annals of the Academy of Medicine, Singapore
JID - 7503289
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Blood Glucose/*analysis
MH  - Fasting/*blood
MH  - Female
MH  - Follow-Up Studies
MH  - *Glucose Tolerance Test/statistics & numerical data
MH  - *Hospitalization
MH  - Humans
MH  - Hyperglycemia/blood/epidemiology
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*blood/complications/epidemiology/therapy
MH  - Prognosis
MH  - Singapore/epidemiology
MH  - Treatment Outcome
EDAT- 1993/05/01 00:00
MHDA- 1993/05/01 00:01
CRDT- 1993/05/01 00:00
PHST- 1993/05/01 00:00 [pubmed]
PHST- 1993/05/01 00:01 [medline]
PHST- 1993/05/01 00:00 [entrez]
PST - ppublish
SO  - Ann Acad Med Singap. 1993 May;22(3):291-5.