PMID- 8404920 OWN - NLM STAT- MEDLINE DCOM- 19931105 LR - 20190830 IS - 0934-9723 (Print) IS - 0934-9723 (Linking) VI - 12 IP - 7 DP - 1993 Jul TI - Duration of specific immunoglobulin A antibody following acute toxoplasmosis as determined by enzyme immunoassay and immunosorbent agglutination assay. PG - 556-9 AB - Modifications of an enzyme immunoassay (EIA) and an immunosorbent agglutination assay (ISAGA) for measuring Toxoplasma gondii-specific IgM antibody were made to enable the measurement of Toxoplasma gondii-specific IgA antibody. It was shown that specific IgA could be measured by both assays but that the ISAGA was slightly more sensitive. IgA appears about two weeks after IgM and persists for 6 to 7 months. However, the IgA response varies considerably both in degree and duration, and demonstration of IgM antibody is at present the most suitable routine test for the diagnosis of recent Toxoplasma gondii infection. FAU - Francis, J M AU - Francis JM AD - Toxoplasma Reference Laboratory, Public Health Laboratory, Singleton Hospital, Swansea, UK. FAU - Joynson, D H AU - Joynson DH LA - eng PT - Journal Article PL - Germany TA - Eur J Clin Microbiol Infect Dis JT - European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology JID - 8804297 RN - 0 (Antibodies, Protozoan) RN - 0 (Immunoglobulin A) RN - 0 (Immunoglobulin M) SB - IM MH - Acute Disease MH - Animals MH - Antibodies, Protozoan/*blood MH - Humans MH - *Immunoenzyme Techniques MH - Immunoglobulin A/*blood MH - Immunoglobulin M/blood MH - *Immunosorbent Techniques MH - Sensitivity and Specificity MH - Toxoplasma/*immunology MH - Toxoplasmosis/*immunology EDAT- 1993/07/01 00:00 MHDA- 1993/07/01 00:01 CRDT- 1993/07/01 00:00 PHST- 1993/07/01 00:00 [pubmed] PHST- 1993/07/01 00:01 [medline] PHST- 1993/07/01 00:00 [entrez] AID - 10.1007/BF01970965 [doi] PST - ppublish SO - Eur J Clin Microbiol Infect Dis. 1993 Jul;12(7):556-9. doi: 10.1007/BF01970965.