PMID- 8423397
OWN - NLM
STAT- MEDLINE
DCOM- 19930219
LR  - 20190723
IS  - 0022-202X (Print)
IS  - 0022-202X (Linking)
VI  - 100
IP  - 1
DP  - 1993 Jan
TI  - Phototesting in lupus erythematosus.
PG  - 53S-57S
AB  - Ultraviolet (UV) irradiation is a major factor in the pathogenesis of certain 
      variants of cutaneous lupus erythematosus. Photosensitivity constitutes one of 
      the criteria of the American Rheumatism Association for the diagnosis of systemic 
      lupus erythematosus, which further emphasizes its importance. The pathomechanism 
      of UV-induced lupus erythematosus remains unknown. The characterization of 
      photosensitive subacute cutaneous lupus erythematosus (SCLE) by Gilliam and 
      Sontheimer has led to a new approach. Through the development of standardized 
      test methods it has became possible to reproduce cutaneous lesions in the UV-A 
      and UV-B spectrum. These standardized test methods allow a better definition of 
      photosensitivity than clinical history does. Recent clinical data show that 
      besides SCLE another variant, lupus erythematosus tumidus, also reveals 
      pronounced photosensitivity. In this review article phototest procedures, 
      phototest results, and clinical correlations in different subgroups are 
      discussed.
FAU - Kind, P
AU  - Kind P
AD  - Department of Dermatology, Ludwig-Maximilians University Munich, F.R.G.
FAU - Lehmann, P
AU  - Lehmann P
FAU - Plewig, G
AU  - Plewig G
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - J Invest Dermatol
JT  - The Journal of investigative dermatology
JID - 0426720
SB  - IM
MH  - Fluorescent Antibody Technique
MH  - Humans
MH  - Immunohistochemistry
MH  - Lupus Erythematosus, Cutaneous/*diagnosis/metabolism/pathology
MH  - *Skin Tests/methods
MH  - *Ultraviolet Rays
RF  - 39
EDAT- 1993/01/01 00:00
MHDA- 1993/01/01 00:01
CRDT- 1993/01/01 00:00
PHST- 1993/01/01 00:00 [pubmed]
PHST- 1993/01/01 00:01 [medline]
PHST- 1993/01/01 00:00 [entrez]
AID - 0022-202X(93)92201-5 [pii]
AID - 10.1111/1523-1747.ep12355594 [doi]
PST - ppublish
SO  - J Invest Dermatol. 1993 Jan;100(1):53S-57S. doi: 10.1111/1523-1747.ep12355594.