PMID- 8434571 OWN - NLM STAT- MEDLINE DCOM- 19930318 LR - 20190512 IS - 0002-9262 (Print) IS - 0002-9262 (Linking) VI - 137 IP - 1 DP - 1993 Jan 1 TI - Prevalence of antibody to human T-cell lymphotropic virus type I in Okinawa, Japan, after an interval of 9 years. PG - 43-8 AB - To clarify events related to age dependence of human T-cell lymphotropic virus type I (HTLV-I) seroprevalence, the authors carried out two seroepidemiologic studies at a 9-year interval on residents of Yonaguni Island, Okinawa, Japan. The overall prevalence was 17.8% (345/1,943) in 1980 and 17.1% (264/1,543) in 1989-1990. The authors studied the relation of the HTLV-I infection rate to the birth year of 967 individuals tested in both years. Of the 967 individuals, 209 were positive for anti-HTLV-I in the 1980 survey. By the 1989-1990 survey, only 7 of the 758 anti-HTLV-I negative cases (0.9%) had become positive for anti-HTLV-I, and all 7 were over 40 years of age. For persons born in the same period, there was almost no difference between the prevalence of HTLV-I found in the 1980 survey and that found in the 1989-1990 survey. These data show that there were few new cases of HTLV-I infection and none in the lower age groups over the 9 years, which suggests that higher rates of HTLV-I infection in adults reflect past higher rates of infection as infants. FAU - Morofuji-Hirata, M AU - Morofuji-Hirata M AD - Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan. FAU - Kajiyama, W AU - Kajiyama W FAU - Nakashima, K AU - Nakashima K FAU - Noguchi, A AU - Noguchi A FAU - Hayashi, J AU - Hayashi J FAU - Kashiwagi, S AU - Kashiwagi S LA - eng PT - Journal Article PL - United States TA - Am J Epidemiol JT - American journal of epidemiology JID - 7910653 RN - 0 (HTLV-I Antibodies) SB - IM MH - Adolescent MH - Adult MH - Age Factors MH - Aged MH - Aged, 80 and over MH - Child MH - Child, Preschool MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - HTLV-I Antibodies/*blood MH - HTLV-I Infections/*epidemiology MH - Humans MH - Infant MH - Japan/epidemiology MH - Male MH - Middle Aged MH - Prevalence MH - Seroepidemiologic Studies MH - Sex Factors EDAT- 1993/01/01 00:00 MHDA- 1993/01/01 00:01 CRDT- 1993/01/01 00:00 PHST- 1993/01/01 00:00 [pubmed] PHST- 1993/01/01 00:01 [medline] PHST- 1993/01/01 00:00 [entrez] AID - 10.1093/oxfordjournals.aje.a116600 [doi] PST - ppublish SO - Am J Epidemiol. 1993 Jan 1;137(1):43-8. doi: 10.1093/oxfordjournals.aje.a116600.