PMID- 8461502
OWN - NLM
STAT- MEDLINE
DCOM- 19930505
LR  - 20190920
IS  - 0886-0440 (Print)
IS  - 0886-0440 (Linking)
VI  - 8
IP  - 2
DP  - 1993 Mar
TI  - Dynamic cardiomyoplasty as an effective therapy for dilated cardiomyopathy.
PG  - 177-83
AB  - Nine male patients with dilated cardiomyopathy unresponsive to maximal medical 
      therapy were submitted to dynamic cardiomyoplasty according to the technique 
      described by Carpentier and Chachques, and preliminary postoperative results are 
      reported. Seven patients were in New York Heart Association (NYHA) Class III and 
      two were in intermittent Class IV. The mean age was 56 years (range 51 to 61 
      years). Preoperative ejection fraction (EF) by multiple gated acquisition ranged 
      from 14% to 28% (mean 20.7%). No additional surgery was performed. 
      Transesophageal echocardiographic monitoring was used during surgery to guide the 
      wrapping procedure. There was no operative mortality. There was one early death 
      (1 month). One late death (sudden death) occurred 7 months after surgery despite 
      significant clinical improvement. Follow-up ranges from 2 to 16 months. Six 
      patients were submitted to hemodynamic evaluation from 4 to 6 months after 
      surgery by transthoracic and transesophageal echo-Doppler assessment. Effective 
      latissimus dorsi support was clearly documented in all patients by comparing 
      postoperative basal hemodynamic values (Cardiomyostimulator [Medtronic, Inc.] 
      switched off) and data obtained during assisted beats (EF increased from 19.4% 
      +/- 8.6% to 32.6% +/- 13.8%, p = 0.043; and stroke volume increased from 51.6 +/- 
      20.6 mL to 63.0 +/- 22.0 mL, p = 0.014). All patients who completed the 
      latissimus dorsi training protocol were in NYHA Class I or II. A significant 
      reduction in postoperative medical therapy was achieved in all patients. Our 
      preliminary results confirm that the cardiomyoplasty procedure is to be 
      considered a safe and valuable mean for treating selected patients with dilated 
      cardiomyopathy refractory to maximal pharmacological treatment.
FAU - Lorusso, R
AU  - Lorusso R
AD  - Department of Cardiac Surgery, Ospedale Civile, Brescia, Italy.
FAU - Zogno, M
AU  - Zogno M
FAU - La Canna, G
AU  - La Canna G
FAU - Metra, M
AU  - Metra M
FAU - Sandrelli, L
AU  - Sandrelli L
FAU - Borghetti, V
AU  - Borghetti V
FAU - Maisano, F
AU  - Maisano F
FAU - Alfieri, O
AU  - Alfieri O
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Card Surg
JT  - Journal of cardiac surgery
JID - 8908809
SB  - IM
MH  - Assisted Circulation/methods
MH  - Cardiac Surgical Procedures/*methods
MH  - Cardiomyopathy, Dilated/diagnostic imaging/physiopathology/*surgery
MH  - Electric Stimulation
MH  - Follow-Up Studies
MH  - Hemodynamics
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Contraction
MH  - Ultrasonography
EDAT- 1993/03/01 00:00
MHDA- 1993/03/01 00:01
CRDT- 1993/03/01 00:00
PHST- 1993/03/01 00:00 [pubmed]
PHST- 1993/03/01 00:01 [medline]
PHST- 1993/03/01 00:00 [entrez]
AID - 10.1111/j.1540-8191.1993.tb00370.x [doi]
PST - ppublish
SO  - J Card Surg. 1993 Mar;8(2):177-83. doi: 10.1111/j.1540-8191.1993.tb00370.x.