PMID- 8465820
OWN - NLM
STAT- MEDLINE
DCOM- 19930504
LR  - 20190815
IS  - 0272-6386 (Print)
IS  - 0272-6386 (Linking)
VI  - 21
IP  - 4
DP  - 1993 Apr
TI  - A prospective comparative study of continuous arteriovenous hemodiafiltration and 
      continuous venovenous hemodiafiltration in critically ill patients.
PG  - 400-4
AB  - We have prospectively studied and compared two consecutive groups of critically 
      ill patients treated with either continuous arteriovenous hemodiafiltration 
      (CAVHD) (n = 28) or continuous venovenous hemodiafiltration (CVVHD) (n = 25) to 
      establish the technique of choice. The two groups were comparable in mean age (59 
      v 58 years), mean Acute Physiology and Chronic Health Evaluation (APACHE) II 
      score (29.6 v 27.4, P = NS), requirements for inotropic drugs, and mean number of 
      failing organs (2.9 v 3.2). CVVHD led to a greater amount of hourly ultrafiltrate 
      (mean, 590 v 424 mL; P < 0.001), but urea and creatinine clearances were not 
      significantly different with the two techniques. Twelve patients survived in the 
      CAVHD group (42.8%) and 13 in the CVVHD group (52%; P = NS). The major advantage 
      for CVVHD use was the substantial decrease in the number of access-related 
      complications (2 v 10; P < 0.025). We conclude that while CVVHD does not offer a 
      significant increase in solute clearance, it significantly minimizes vascular 
      access-related morbidity and should therefore be regarded as the therapeutic 
      modality of choice.
FAU - Bellomo, R
AU  - Bellomo R
AD  - Monash Medical Centre, Clayton, Victoria, Australia.
FAU - Parkin, G
AU  - Parkin G
FAU - Love, J
AU  - Love J
FAU - Boyce, N
AU  - Boyce N
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Am J Kidney Dis
JT  - American journal of kidney diseases : the official journal of the National Kidney 
      Foundation
JID - 8110075
RN  - 8W8T17847W (Urea)
RN  - AYI8EX34EU (Creatinine)
SB  - IM
MH  - Chi-Square Distribution
MH  - Creatinine/blood
MH  - Critical Care/methods
MH  - Critical Illness
MH  - Female
MH  - Hemofiltration/*methods
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Renal Dialysis/*methods
MH  - Urea/blood
EDAT- 1993/04/01 00:00
MHDA- 1993/04/01 00:01
CRDT- 1993/04/01 00:00
PHST- 1993/04/01 00:00 [pubmed]
PHST- 1993/04/01 00:01 [medline]
PHST- 1993/04/01 00:00 [entrez]
AID - S0272638693000617 [pii]
AID - 10.1016/s0272-6386(12)80268-x [doi]
PST - ppublish
SO  - Am J Kidney Dis. 1993 Apr;21(4):400-4. doi: 10.1016/s0272-6386(12)80268-x.