PMID- 8468047
OWN - NLM
STAT- MEDLINE
DCOM- 19930511
LR  - 20181130
IS  - 0888-7543 (Print)
IS  - 0888-7543 (Linking)
VI  - 15
IP  - 3
DP  - 1993 Mar
TI  - High-resolution chromosomal localization of the human calcitonin/CGRP/IAPP gene 
      family members.
PG  - 525-9
AB  - We report the high-resolution localization of the human calcitonin/CGRP genes, 
      CALCA, CALCB, and the pseudogene CALCP, to a 220-kb SacII fragment on chromosome 
      11p15.2-p15.1, using prometaphase fluorescence in situ hybridization (FISH), 
      two-color interphase FISH, and pulsed-field gel electrophoresis analysis. The 
      related islet amyloid polypeptide (IAPP) gene was assigned to human chromosome 
      12p12.3-p12.1. The results support an evolutionary relationship between the 
      calcitonin/CGRP genes and the IAPP gene and between parts of human chromosomes 11 
      and 12.
FAU - Hoovers, J M
AU  - Hoovers JM
AD  - Institute of Human Genetics, University of Amsterdam, The Netherlands.
FAU - Redeker, E
AU  - Redeker E
FAU - Speleman, F
AU  - Speleman F
FAU - Hoppener, J W
AU  - Hoppener JW
FAU - Bhola, S
AU  - Bhola S
FAU - Bliek, J
AU  - Bliek J
FAU - van Roy, N
AU  - van Roy N
FAU - Leschot, N J
AU  - Leschot NJ
FAU - Westerveld, A
AU  - Westerveld A
FAU - Mannens, M
AU  - Mannens M
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Genomics
JT  - Genomics
JID - 8800135
RN  - 0 (Amyloid)
RN  - 0 (Islet Amyloid Polypeptide)
RN  - 9007-12-9 (Calcitonin)
RN  - JHB2QIZ69Z (Calcitonin Gene-Related Peptide)
SB  - IM
GS  - CALCA
GS  - CALCB
GS  - CALCP
GS  - CGRP
GS  - IAPP
MH  - Amyloid/*genetics
MH  - Calcitonin/*genetics
MH  - Calcitonin Gene-Related Peptide/*genetics
MH  - Chromosome Mapping
MH  - *Chromosomes, Human, Pair 11
MH  - *Chromosomes, Human, Pair 12
MH  - Electrophoresis, Gel, Pulsed-Field
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Islet Amyloid Polypeptide
MH  - Multigene Family
MH  - Tumor Cells, Cultured
EDAT- 1993/03/01 00:00
MHDA- 1993/03/01 00:01
CRDT- 1993/03/01 00:00
PHST- 1993/03/01 00:00 [pubmed]
PHST- 1993/03/01 00:01 [medline]
PHST- 1993/03/01 00:00 [entrez]
AID - S0888-7543(83)71104-3 [pii]
AID - 10.1006/geno.1993.1104 [doi]
PST - ppublish
SO  - Genomics. 1993 Mar;15(3):525-9. doi: 10.1006/geno.1993.1104.