PMID- 8499913
OWN - NLM
STAT- MEDLINE
DCOM- 19930629
LR  - 20220129
IS  - 0964-6906 (Print)
IS  - 0964-6906 (Linking)
VI  - 2
IP  - 3
DP  - 1993 Mar
TI  - The organization and conservation of the human Surfeit gene cluster and its 
      localization telomeric to the c-abl and can proto-oncogenes at chromosome band 
      9q34.1.
PG  - 237-40
AB  - The mouse Surfeit locus contains an unusually tight cluster of six housekeeping 
      genes (Surf-1 to -6) which are unrelated by sequence homology. Using a mouse 
      Surfeit locus probe, a 16 kb clone has been isolated which contains the human 
      Surf-1 and Surf-3 genes and regions of the human Surf-2 and Surf-5 genes. The 
      organization and juxtaposition of these human Surfeit locus genes are the same as 
      found in the mouse. Using the human clone as a biotinylated probe for 
      fluorescence in situ hybridization (FISH) we have confirmed the location of the 
      human Surfeit locus to chromosome band 9q34. Metaphase spreads of human chronic 
      myeloid leukemic cells containing the t(9;22)(q34;q11) translocation involving 
      The c-abl gene at 9q34.1 an acute nonlymphocytic leukemic cells containing the 
      t(6;9)(q34;p23) translocation involving the can gene at 9q34.1 were analyzed by 
      FISH using the human Surfeit clone as a probe. These analyses locate the human 
      Surfeit locus telomeric to the c-abl and can genes at chromosome band 9q34.1.
FAU - Yon, J
AU  - Yon J
AD  - Eukaryotic Gene Organization Laboratory, Imperial Cancer Research Fund, London, 
      UK.
FAU - Jones, T
AU  - Jones T
FAU - Garson, K
AU  - Garson K
FAU - Sheer, D
AU  - Sheer D
FAU - Fried, M
AU  - Fried M
LA  - eng
GR  - A3585/CRUK_/Cancer Research UK/United Kingdom
PT  - Comparative Study
PT  - Journal Article
PL  - England
TA  - Hum Mol Genet
JT  - Human molecular genetics
JID - 9208958
RN  - 0 (DNA Probes)
RN  - 9007-49-2 (DNA)
SB  - IM
GS  - c-abl
GS  - can
MH  - Animals
MH  - Base Sequence
MH  - Chromosome Mapping
MH  - *Chromosomes, Human, Pair 8
MH  - *Conserved Sequence
MH  - Cosmids
MH  - DNA/genetics
MH  - DNA Probes
MH  - Genes, abl
MH  - Humans
MH  - Mice
MH  - *Multigene Family
MH  - Proto-Oncogenes
MH  - Species Specificity
EDAT- 1993/03/01 00:00
MHDA- 1993/03/01 00:01
CRDT- 1993/03/01 00:00
PHST- 1993/03/01 00:00 [pubmed]
PHST- 1993/03/01 00:01 [medline]
PHST- 1993/03/01 00:00 [entrez]
AID - 10.1093/hmg/2.3.237 [doi]
PST - ppublish
SO  - Hum Mol Genet. 1993 Mar;2(3):237-40. doi: 10.1093/hmg/2.3.237.