PMID- 8517792
OWN - NLM
STAT- MEDLINE
DCOM- 19930721
LR  - 20190815
IS  - 0304-8608 (Print)
IS  - 0304-8608 (Linking)
VI  - 130
IP  - 3-4
DP  - 1993
TI  - The prevalence of antibodies to human T-lymphotropic virus type I in different 
      population groups in Papua New Guinea.
PG  - 327-34
AB  - Isolation and partial sequencing of human T-lymphotropic virus type I (HTLV-I) 
      variants from inhabitants of Papua New Guinea (PNG) and the Solomon Islands has 
      confirmed the existence of virus infection in Melanesian populations. To 
      determine the geographical distribution of seropositivity to HTLV-I in PNG we 
      have tested 2907 serum and plasma samples collected between 1972 to 1991 from 16 
      different population groups. Samples were screened using a particle agglutination 
      assay and confirmed by p21e-enhanced Western immunoblot (WB). From a total of 94 
      screen positive samples run on WB, 56 (60%) were confirmed positive (positive for 
      both env and gag products) and 38 (40%) were WB-indeterminate (gag products 
      only). The prevalence of WB-confirmed antibodies to HTLV-I in lowland and island 
      populations ranged from 0 to 5.4%. There were no confirmed antibody positives in 
      the highland populations surveyed. Geographically isolated populations living on 
      the fringes of the highlands ranged in seropositivity from 0.2 to 5.8%. Two of 
      the subjects surveyed gave WB antibody patterns characteristic of HTLV-II rather 
      than HTLV-I infection.
FAU - Sanders, R C
AU  - Sanders RC
AD  - Papua New Guinea Institute of Medical Research, Goroka.
FAU - Wai'in, P M
AU  - Wai'in PM
FAU - Alexander, S S
AU  - Alexander SS
FAU - Levin, A G
AU  - Levin AG
FAU - Blattner, W A
AU  - Blattner WA
FAU - Alpers, M P
AU  - Alpers MP
LA  - eng
GR  - N01-CP-85603/CP/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Austria
TA  - Arch Virol
JT  - Archives of virology
JID - 7506870
RN  - 0 (HTLV-I Antibodies)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Agglutination Tests
MH  - Blotting, Western
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - HTLV-I Antibodies/*blood
MH  - HTLV-I Infections/*epidemiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Papua New Guinea/epidemiology
MH  - Prevalence
MH  - Seroepidemiologic Studies
EDAT- 1993/01/01 00:00
MHDA- 1993/01/01 00:01
CRDT- 1993/01/01 00:00
PHST- 1993/01/01 00:00 [pubmed]
PHST- 1993/01/01 00:01 [medline]
PHST- 1993/01/01 00:00 [entrez]
AID - 10.1007/BF01309664 [doi]
PST - ppublish
SO  - Arch Virol. 1993;130(3-4):327-34. doi: 10.1007/BF01309664.