PMID- 8521727
OWN - NLM
STAT- MEDLINE
DCOM- 19960122
LR  - 20180214
IS  - 0301-0171 (Print)
IS  - 0301-0171 (Linking)
VI  - 71
IP  - 4
DP  - 1995
TI  - Regional assignment of the human 4-hydroxyphenylpyruvate dioxygenase gene (HPD) 
      to 12q24-->qter by fluorescence in situ hybridization.
PG  - 374-6
AB  - Using a panel of human-rodent somatic cell hybrids, we have previously mapped the 
      gene (HPD, previously called PPD) encoding 4-hydroxyphenylpyruvate dioxygenase to 
      the distal half of the long arm of human chromosome 12, region q14-->qter. To 
      obtain a genomic probe useful for fluorescence in situ hybridization (FISH) 
      analysis we screened a human leukocyte genomic library and isolated a 13.4-kb 
      phage clone, which by restriction fragment and sequence analyses was shown to 
      contain exons 1-10 of HPD and approximately 2-kb upstream sequences. We now 
      report the subregional localization of HPD to 12q24-->qter based on two color 
      FISH analysis employing this clone.
FAU - Stenman, G
AU  - Stenman G
AD  - Laboratory of Cancer Genetics, Department of Pathology, Goteborg University, 
      Sweden.
FAU - Roijer, E
AU  - Roijer E
FAU - Ruetschi, U
AU  - Ruetschi U
FAU - Dellsen, A
AU  - Dellsen A
FAU - Rymo, L
AU  - Rymo L
FAU - Lindstedt, S
AU  - Lindstedt S
LA  - eng
SI  - GENBANK/U29895
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Switzerland
TA  - Cytogenet Cell Genet
JT  - Cytogenetics and cell genetics
JID - 0367735
RN  - 0 (DNA, Complementary)
RN  - EC 1.13.11.27 (4-Hydroxyphenylpyruvate Dioxygenase)
SB  - IM
MH  - 4-Hydroxyphenylpyruvate Dioxygenase/*genetics
MH  - Animals
MH  - Base Sequence
MH  - Blotting, Southern
MH  - Chromosome Mapping
MH  - Chromosomes, Human, Pair 12/*genetics/ultrastructure
MH  - DNA, Complementary
MH  - Exons/genetics
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Mice
MH  - Molecular Sequence Data
EDAT- 1995/01/01 00:00
MHDA- 1995/01/01 00:01
CRDT- 1995/01/01 00:00
PHST- 1995/01/01 00:00 [pubmed]
PHST- 1995/01/01 00:01 [medline]
PHST- 1995/01/01 00:00 [entrez]
AID - 10.1159/000134142 [doi]
PST - ppublish
SO  - Cytogenet Cell Genet. 1995;71(4):374-6. doi: 10.1159/000134142.