PMID- 8530723
OWN - NLM
STAT- MEDLINE
DCOM- 19960130
LR  - 20190914
IS  - 0300-5712 (Print)
IS  - 0300-5712 (Linking)
VI  - 23
IP  - 6
DP  - 1995 Dec
TI  - Seroepidemiology of herpes virus infections among dental personnel.
PG  - 339-42
AB  - OBJECTIVES: To examine the possible occupational hazard of infection with human 
      herpes viruses among dental personnel. METHODS: Sera from 81 preclinical dental 
      students, 53 clinical dental students and 103 qualified dental surgeons were 
      tested for antibodies to herpes simplex virus type 1 (HSV-1), cytomegalovirus 
      (CMV), Epstein-Barr virus (EBV) and human herpes virus type 6 (HHV-6). The same 
      number of control subjects, matched individually for age (+/- 1 year), sex and 
      social class, was also examined. Antibodies were detected by ELISA for HSV-1, 
      latex agglutination for CMV, indirect immunofluorescence with P3HR1 cells for EBV 
      and indirect immunofluorescence with infected JJhan cells for HHV-6. Each 
      participant also completed a questionnaire to permit correlation of demographic 
      data and risk factors with serological results. RESULTS: No significant 
      difference in seroprevalence was detected between any of the dental groups and 
      their respective controls. There was a significantly higher prevalence of 
      antibodies to EBV among clinical students (P = 0.02) and qualified dentists (P = 
      0.0003) than among preclinical students. These significant increases were not 
      mirrored in the three corresponding control groups. CONCLUSION: The results 
      suggest a possible occupational risk of infection with EBV in dentists. There was 
      no evidence for a significant risk of occupational infection with HSV-1, CMV or 
      HHV-6.
FAU - Herbert, A M
AU  - Herbert AM
AD  - Department of Oral Surgery, Medicine and Pathology, Cardiff Dental School, UK.
FAU - Bagg, J
AU  - Bagg J
FAU - Walker, D M
AU  - Walker DM
FAU - Davies, K J
AU  - Davies KJ
FAU - Westmoreland, D
AU  - Westmoreland D
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Dent
JT  - Journal of dentistry
JID - 0354422
RN  - 0 (Antibodies, Viral)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Antibodies, Viral/*blood
MH  - Case-Control Studies
MH  - Cytomegalovirus/immunology
MH  - Cytomegalovirus Infections/blood/immunology
MH  - *Dentists
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Female
MH  - Fluorescent Antibody Technique, Indirect
MH  - Herpes Simplex/blood/immunology
MH  - Herpesviridae Infections/*blood/immunology/prevention & control
MH  - Herpesvirus 1, Human/immunology
MH  - Herpesvirus 4, Human/immunology
MH  - Herpesvirus 6, Human/immunology
MH  - Humans
MH  - Latex Fixation Tests
MH  - Male
MH  - Middle Aged
MH  - Occupational Diseases/*blood/immunology/prevention & control
MH  - Risk Factors
MH  - Seroepidemiologic Studies
MH  - Social Class
MH  - *Students, Dental
MH  - Tumor Virus Infections/blood/immunology
EDAT- 1995/12/01 00:00
MHDA- 1995/12/01 00:01
CRDT- 1995/12/01 00:00
PHST- 1995/12/01 00:00 [pubmed]
PHST- 1995/12/01 00:01 [medline]
PHST- 1995/12/01 00:00 [entrez]
AID - 030057129400017A [pii]
AID - 10.1016/0300-5712(94)00017-a [doi]
PST - ppublish
SO  - J Dent. 1995 Dec;23(6):339-42. doi: 10.1016/0300-5712(94)00017-a.