PMID- 8541370
OWN - NLM
STAT- MEDLINE
DCOM- 19960213
LR  - 20220317
IS  - 0394-9532 (Print)
IS  - 0394-9532 (Linking)
VI  - 7
IP  - 4
DP  - 1995 Aug
TI  - Colonic investigations in the elderly: colonoscopy or barium enema?
PG  - 190-4
AB  - Colonoscopy (CS) is currently considered the best diagnostic procedure for 
      colonic imaging. The objectives of this multicentric study were to assess whether 
      CS or simple contrast barium enema (SCBE) has the best effectiveness and 
      tolerance in the elderly (over 80 years old). Except in cases of emergency, 67 
      elderly patients from 3 centers were randomized among three diagnostic 
      strategies: CS, SCBE or barium enema+rectosigmoidoscopy (BERS). CSs were 
      generally carried out after polyethylene-glycol (PEG) cleansing, and barium 
      enemas after enema cleansing. The diagnostic effectiveness of the three 
      strategies was not significantly different: a colonic abnormality was found in 
      CS, SCBE, BERS groups in 65, 56 and 71% of the cases, respectively. No other 
      investigation was needed in 61 to 76% of cases, and, on the basis of the 
      exploration, final therapy was modified in less than 22% of cases. Overall 
      cleansing quality was significantly better with barium enema (84.1%) than with CS 
      (57.0%; p < 0.05). This was explained by a poor tolerance to PEG intake, which 
      led to 28.2% of adverse effects, compared with 7.1% after enema preparation (p < 
      0.05). This resulted in a significantly higher failure rate of complete colonic 
      exploration with CS (48%) than with barium enema (9%; p < 0.001). In conclusion, 
      the effectiveness of the three diagnostic strategies is similar in the elderly. 
      However, due to a better acceptance of the enema preparation, and to a better 
      success rate of complete exploration, SCBE should be preferred to investigate 
      colonic symptoms when the above preparations are used.
FAU - Burtin, P
AU  - Burtin P
AD  - Gastroenterology Unit, University Hospital, Angers, France.
FAU - Bour, B
AU  - Bour B
FAU - Charlois, T
AU  - Charlois T
FAU - Ruget, O
AU  - Ruget O
FAU - Cales, P
AU  - Cales P
FAU - Dauver, A
AU  - Dauver A
FAU - Boyer, J
AU  - Boyer J
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
PL  - Italy
TA  - Aging (Milano)
JT  - Aging (Milan, Italy)
JID - 9102503
RN  - 24GP945V5T (Barium)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - *Aging
MH  - *Barium/administration & dosage
MH  - Colon/diagnostic imaging/pathology
MH  - Colonic Diseases/*diagnosis
MH  - *Colonoscopy
MH  - Enema
MH  - Evaluation Studies as Topic
MH  - Female
MH  - Humans
MH  - Length of Stay
MH  - Male
MH  - Radiography
MH  - Rectum/pathology
MH  - Sigmoidoscopy
EDAT- 1995/08/01 00:00
MHDA- 1995/08/01 00:01
CRDT- 1995/08/01 00:00
PHST- 1995/08/01 00:00 [pubmed]
PHST- 1995/08/01 00:01 [medline]
PHST- 1995/08/01 00:00 [entrez]
AID - 10.1007/BF03324334 [doi]
PST - ppublish
SO  - Aging (Milano). 1995 Aug;7(4):190-4. doi: 10.1007/BF03324334.