PMID- 8542426 OWN - NLM STAT- MEDLINE DCOM- 19960212 LR - 20121115 IS - 0969-7128 (Print) IS - 0969-7128 (Linking) VI - 1 Suppl 1 DP - 1994 TI - Adeno-associated virus (AAV) as a vector for gene transfer into glial cells of the human central nervous system. PG - S80 AB - To examine the potential of AAV as a vector for gene transfer in glial cells, an established astrocytoma cell line and short-term cultures derived from human oligodendroglioma have been coinfected with AAV and helper adenovirus. The level of AAV replication in glioma cells was high indicating that they express receptors for AAV. FAU - Tenenbaum, L AU - Tenenbaum L AD - Laboratory of Pharmacology, Free University of Brussels, Belgium. FAU - Darling, J L AU - Darling JL FAU - Hooghe-Peters, E AU - Hooghe-Peters E LA - eng PT - Journal Article PL - England TA - Gene Ther JT - Gene therapy JID - 9421525 SB - IM MH - Astrocytoma/therapy/*virology MH - Brain Neoplasms/therapy/*virology MH - Dependovirus/*genetics/physiology MH - *Gene Transfer Techniques MH - Genetic Therapy MH - *Genetic Vectors MH - Humans MH - Oligodendroglioma/therapy/virology MH - Tumor Cells, Cultured MH - Virus Replication EDAT- 1994/01/01 00:00 MHDA- 1994/01/01 00:01 CRDT- 1994/01/01 00:00 PHST- 1994/01/01 00:00 [pubmed] PHST- 1994/01/01 00:01 [medline] PHST- 1994/01/01 00:00 [entrez] PST - ppublish SO - Gene Ther. 1994;1 Suppl 1:S80.