PMID- 8551683 OWN - NLM STAT- MEDLINE DCOM- 19960220 LR - 20151119 IS - 0047-1860 (Print) IS - 0047-1860 (Linking) VI - 43 IP - 11 DP - 1995 Nov TI - [Hand-mirror cells acute lymphoblastic leukemia (L3)]. PG - 1173-7 AB - To our knowledge, this report represents the first confirmed case in Japan of a 15-year-old boy with acute lymphoblastic leukemia (ALL).L3 with hand-mirror cells (HMC) in the bone marrow. HMC lymphoid leukemia is an unusual variant of ALL in which the bone marrow lymphoblasts manifest distinctive hand-mirror morphologic features. HMC lymphoblast is characterized by an asymmetric foot-like cytoplasmic process that extends from the portion of the cell, thus giving it the light-microscopic appearance responsible for its name. Besides ALL, HMC has been reported in acute myeloblastic leukemia (AML), blastic crisis of chronic myelogenous leukemia, non-Hodgkin's lymphoma, and infectious mononucleosis. HMC has been reported to be prevalent in ALL.L1 and L2 as compared with L3. FAU - Uemura, K AU - Uemura K AD - Central Clinical Laboratory, University of Occupational and Environmental Health, Kitakyusyu. FAU - Otani, H AU - Otani H FAU - Sakamoto, K AU - Sakamoto K FAU - Sakanishi, Y AU - Sakanishi Y FAU - Ota, T AU - Ota T FAU - Kobayashi, T AU - Kobayashi T FAU - Ariyoshi, N AU - Ariyoshi N FAU - Shirahata, A AU - Shirahata A LA - jpn PT - Case Reports PT - English Abstract PT - Journal Article PT - Review PL - Japan TA - Rinsho Byori JT - Rinsho byori. The Japanese journal of clinical pathology JID - 2984781R RN - 5J49Q6B70F (Vincristine) RN - 80168379AG (Doxorubicin) RN - 9PHQ9Y1OLM (Prednisolone) SB - IM MH - Adolescent MH - Antineoplastic Combined Chemotherapy Protocols/therapeutic use MH - Blast Crisis MH - *Bone Marrow Cells MH - Doxorubicin/administration & dosage MH - Fatal Outcome MH - Humans MH - Male MH - Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy/*pathology MH - Prednisolone/administration & dosage MH - Remission Induction MH - Vincristine/administration & dosage RF - 24 EDAT- 1995/11/01 00:00 MHDA- 1995/11/01 00:01 CRDT- 1995/11/01 00:00 PHST- 1995/11/01 00:00 [pubmed] PHST- 1995/11/01 00:01 [medline] PHST- 1995/11/01 00:00 [entrez] PST - ppublish SO - Rinsho Byori. 1995 Nov;43(11):1173-7.