PMID- 8555613
OWN - NLM
STAT- MEDLINE
DCOM- 19960226
LR  - 20201209
IS  - 1058-2916 (Print)
IS  - 1058-2916 (Linking)
VI  - 40
IP  - 3
DP  - 1994 Jul-Sep
TI  - Vibration analysis of vessel wall motion with intra vena caval balloon pumping.
PG  - M740-2
AB  - The intravenous membrane oxygenator (IMO) incorporates a centrally positioned 
      balloon surrounded by hollow microporous fibers. Previous studies using this 
      configuration have demonstrated that rhythmic pulsation of the balloon enhances 
      gas exchange, presumably by three dimensional convective mixing. This study 
      sought to characterize vessel wall vibrations imparted by intra vena caval 
      balloon pumping. An in vitro flow loop incorporating a current IMO prototype was 
      used for these measurements. The IMO prototype was inserted in a modeled vena 
      cava on which ultrasonic dimension transducers were mounted on the outer surface. 
      The flow loop was operated at physiologic flow rates. The balloon was activated, 
      and dynamic vessel diameter measurements were recorded as the pumping frequency 
      was varied from 40 to 120 beats per minute (bpm). A Fast Fourier Transform 
      algorithm generated a frequency spectrum at each bpm and for two different 
      balloon configurations; a single balloon versus a tripartite arrangement, the 
      authors' results demonstrate that the mean amplitude of vena caval oscillations 
      varied with bpm, and that this variation followed the trends in oxygen transfer 
      rates. This suggests that the motion of the vessel wall may contribute to 
      convective mixing of blood. In addition, this work demonstrated significant 
      differences in the frequency spectra associated with our two balloon 
      configurations.
FAU - Shafi, A S
AU  - Shafi AS
AD  - Department of Surgery, University of Pittsburgh Medical Center, PA 15213-2582, 
      USA.
FAU - Lund, L W
AU  - Lund LW
FAU - Walters, F R
AU  - Walters FR
FAU - Sawzik, P J
AU  - Sawzik PJ
FAU - Reeder, G D
AU  - Reeder GD
FAU - Borovetz, H S
AU  - Borovetz HS
FAU - Hattler, B G
AU  - Hattler BG
LA  - eng
GR  - R43 HL-49026/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - ASAIO J
JT  - ASAIO journal (American Society for Artificial Internal Organs : 1992)
JID - 9204109
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Biomechanical Phenomena
MH  - Evaluation Studies as Topic
MH  - Humans
MH  - In Vitro Techniques
MH  - Oscillometry
MH  - Oxygen/blood
MH  - *Oxygenators, Membrane
MH  - Respiratory Distress Syndrome/blood/therapy
MH  - Venae Cavae/physiology
MH  - Vibration
EDAT- 1994/07/01 00:00
MHDA- 1994/07/01 00:01
CRDT- 1994/07/01 00:00
PHST- 1994/07/01 00:00 [pubmed]
PHST- 1994/07/01 00:01 [medline]
PHST- 1994/07/01 00:00 [entrez]
AID - 10.1097/00002480-199407000-00097 [doi]
PST - ppublish
SO  - ASAIO J. 1994 Jul-Sep;40(3):M740-2. doi: 10.1097/00002480-199407000-00097.