PMID- 8560792
OWN - NLM
STAT- MEDLINE
DCOM- 19960226
LR  - 20190728
IS  - 0042-6989 (Print)
IS  - 0042-6989 (Linking)
VI  - 35
IP  - 23-24
DP  - 1995 Dec
TI  - Are laws that govern behavior embedded in the structure of the CNS? The case of 
      Hering's law.
PG  - 3207-16
AB  - The pattern of axonal terminations of individual premotoneuronal medium lead 
      burst neurons (MLBs) has been elucidated with the help of the intraaxonal 
      recording and horseradish peroxidase injection technique in alert behaving 
      monkeys. These findings indicate that individual MLBs do not influence individual 
      muscles; instead they influence groups of muscles. Horizontal medium lead burst 
      neurons (EBNs) project to ipsilateral lateral rectus motoneurons directly, and 
      could contact contralateral medial rectus motoneurons indirectly, through the 
      internuclear neurons of the ipsilateral abducens nucleus. Also, upward MLBs 
      project to motoneurons innervating both the superior rectus and the inferior 
      oblique muscles of both eyes. Finally, downward MLBs project to ipsilateral 
      motoneurons innervating the ipsilateral inferior rectus muscle and the 
      contralateral superior oblique muscle. All in all, the pattern of oculomotor 
      terminations of MLBs provides experimental support for Hering's law of equal 
      innervation. EBNs also project to the nucleus prepositus hypoglossi while 
      vertical MLBs also project to the interstitial nucleus of Cajal (NIC). These 
      structures are thought to participate in the process of "velocity to position 
      integration", in the horizontal and vertical planes respectively. Intracellular 
      recording from individual neurons of the NIC in alert behaving monkeys followed 
      by biocytin or horseradish peroxidase injections demonstrates that their axons 
      pass through the posterior commissure on their way to vertical extraocular 
      motoneurons. It also demonstrates that these fibers carry a phasic signal related 
      to saccades and a tonic signal related to eye position in a precise quantitative 
      manner. Work is in progress to determine whether their pattern of oculomotor 
      terminations is also appropriate for Hering's law.
FAU - Moschovakis, A K
AU  - Moschovakis AK
AD  - Department of Basic Sciences, Faculty of Medicine, School of Health Sciences, 
      University of Crete, Iraklion, Greece.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Vision Res
JT  - Vision research
JID - 0417402
SB  - IM
MH  - Abducens Nerve/anatomy & histology
MH  - Action Potentials/physiology
MH  - Animals
MH  - Axons/physiology
MH  - Brain/anatomy & histology
MH  - Motor Neurons/physiology
MH  - Nerve Net/anatomy & histology
MH  - Neural Pathways
MH  - Oculomotor Muscles/*innervation
MH  - Saccades/*physiology
MH  - Saimiri
EDAT- 1995/12/01 00:00
MHDA- 1995/12/01 00:01
CRDT- 1995/12/01 00:00
PHST- 1995/12/01 00:00 [pubmed]
PHST- 1995/12/01 00:01 [medline]
PHST- 1995/12/01 00:00 [entrez]
AID - 0042-6989(95)00133-Y [pii]
AID - 10.1016/0042-6989(95)00133-y [doi]
PST - ppublish
SO  - Vision Res. 1995 Dec;35(23-24):3207-16. doi: 10.1016/0042-6989(95)00133-y.