PMID- 856329
OWN - NLM
STAT- MEDLINE
DCOM- 19770611
LR  - 20161123
IS  - 0365-9615 (Print)
IS  - 0365-9615 (Linking)
VI  - 83
IP  - 1
DP  - 1977 Jan
TI  - [Dynamics of changes in hexokinase activity in subcellular tissue fractions of 
      hypoxic newborn rats].
PG  - 21-4
AB  - The activity of hexokinase (HK) in the total homogenate, cytoplasmic and 
      mitochondrial fractions of the brain, heart and liver of the newborn rats was 
      studied in relation to the severity of the hypoxic action. A mild from of hypoxic 
      hypoxia caused in the tissue of the brain and liver an increase in the activity 
      of mitochondrial-bound form of the enzyme with a simultaneous fall in the 
      activity of the cytoplasmic HK; this was accompanied by a marked acceleration of 
      glucose phosphorylation in the brain. Severe hypoxia led to the reduction of the 
      HK activity in the total homogenate and both intracellular fractions in all the 
      tissues under study. The data obtained pointed to disturbance of some adaptive 
      mechanisms in severe hypoxia in the tissues of the newborn rats.
FAU - Ignatiuk, T E
AU  - Ignatiuk TE
LA  - rus
PT  - Journal Article
TT  - Dinamika izmenenii aktivnosti geksokinazy v subkletochnykh fraktsiiakh tkanei 
      novorozhdennykh krysiat pri gipoksii.
PL  - Russia (Federation)
TA  - Biull Eksp Biol Med
JT  - Biulleten' eksperimental'noi biologii i meditsiny
JID - 0370627
RN  - 0 (Glucosephosphates)
RN  - EC 2.7.1.1 (Hexokinase)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Animals
MH  - *Animals, Newborn
MH  - Brain/enzymology/ultrastructure
MH  - Cytoplasm/enzymology
MH  - Glucose/metabolism
MH  - Glucosephosphates/metabolism
MH  - Hexokinase/*metabolism
MH  - Hypoxia/*enzymology/metabolism
MH  - Liver/enzymology/ultrastructure
MH  - Mitochondria/enzymology
MH  - Myocardium/enzymology/ultrastructure
MH  - Rats
EDAT- 1977/01/01 00:00
MHDA- 1977/01/01 00:01
CRDT- 1977/01/01 00:00
PHST- 1977/01/01 00:00 [pubmed]
PHST- 1977/01/01 00:01 [medline]
PHST- 1977/01/01 00:00 [entrez]
PST - ppublish
SO  - Biull Eksp Biol Med. 1977 Jan;83(1):21-4.