PMID- 8567509
OWN - NLM
STAT- MEDLINE
DCOM- 19960307
LR  - 20171213
IS  - 8750-7587 (Print)
IS  - 0161-7567 (Linking)
VI  - 79
IP  - 3
DP  - 1995 Sep
TI  - Oxidation of exogenous [13C]galactose and [13C]glucose during exercise.
PG  - 720-5
AB  - The present study examined the oxidation of exogenous galactose or glucose during 
      prolonged submaximal cycling exercise. Eight highly trained volunteers exercised 
      on two occasions on a cycle ergometer at 65% of maximal workload for 120 min, 
      followed by a 60-min rest period and a second exercise bout of 30 min at 60% 
      maximal workload. At random, subjects ingested a 8% galactose solution to which 
      an [1-13C]galactose tracer was added or a 8% glucose solution to which an 
      [U-13C]glucose tracer was added. Drinks were provided at the end of the warm-up 
      period (8 ml/kg) and every 15 min (2 ml/kg) during the first 120 min of the test. 
      Blood and breath samples were collected every 30 and 15 min, respectively, during 
      the test. The exogenous carbohydrate (CHO) oxidation was calculated from the 
      13CO2/12CO2 ratio and CO2 production of the expired air. Peak exogenous CHO 
      oxidation during exercise for galactose and glucose was 0.41 +/- 0.03 and 0.85 
      +/- 0.04 g/min, respectively. Total CHO and fat oxidation were not significantly 
      different between the treatments. Forty-six percent of the ingested glucose was 
      oxidized, whereas only 21% of the ingested galactose was oxidized. As a 
      consequence, more endogenous CHO was utilized with galactose than with glucose 
      (124.4 +/- 6.7 and 100.1 +/- 3.6 g, respectively). These results indicate that 
      the oxidation rate of orally ingested galactose is maximally approximately 50% of 
      the oxidation rate of a comparable amount of orally ingested glucose during 120 
      min of exercise.
FAU - Leijssen, D P
AU  - Leijssen DP
AD  - Department of Human Biology, University of Limburg, Maastricht, The Netherlands.
FAU - Saris, W H
AU  - Saris WH
FAU - Jeukendrup, A E
AU  - Jeukendrup AE
FAU - Wagenmakers, A J
AU  - Wagenmakers AJ
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Appl Physiol (1985)
JT  - Journal of applied physiology (Bethesda, Md. : 1985)
JID - 8502536
RN  - 0 (Carbon Isotopes)
RN  - 0 (Insulin)
RN  - 0 (Lactates)
RN  - 33X04XA5AT (Lactic Acid)
RN  - IY9XDZ35W2 (Glucose)
RN  - X2RN3Q8DNE (Galactose)
SB  - IM
MH  - Administration, Oral
MH  - Adult
MH  - *Carbohydrate Metabolism
MH  - Carbon Isotopes
MH  - Double-Blind Method
MH  - Exercise/*physiology
MH  - Galactose/administration & dosage/*pharmacokinetics
MH  - Glucose/administration & dosage/*pharmacokinetics
MH  - Humans
MH  - Insulin/blood
MH  - Lactates/blood
MH  - Lactic Acid
MH  - Male
MH  - Muscle, Skeletal/metabolism
MH  - Oxidation-Reduction
EDAT- 1995/09/01 00:00
MHDA- 1995/09/01 00:01
CRDT- 1995/09/01 00:00
PHST- 1995/09/01 00:00 [pubmed]
PHST- 1995/09/01 00:01 [medline]
PHST- 1995/09/01 00:00 [entrez]
AID - 10.1152/jappl.1995.79.3.720 [doi]
PST - ppublish
SO  - J Appl Physiol (1985). 1995 Sep;79(3):720-5. doi: 10.1152/jappl.1995.79.3.720.