PMID- 8567514
OWN - NLM
STAT- MEDLINE
DCOM- 19960307
LR  - 20171213
IS  - 8750-7587 (Print)
IS  - 0161-7567 (Linking)
VI  - 79
IP  - 3
DP  - 1995 Sep
TI  - Metabolic availability of medium-chain triglycerides coingested with 
      carbohydrates during prolonged exercise.
PG  - 756-62
AB  - The present study examined the metabolic response to medium-chain triglycerides 
      (MCTs) ingestion with or without carbohydrates (CHOs). Eight well-trained 
      athletes cycled 4 x 180 min at 50% maximal work rate (57% maximal O2 
      consumption). Subjects drank a bolus of 4 ml/kg at the start and 2 ml/kg every 20 
      min during exercise of either a 15% (214 g) CHO solution (CHO trial), an 
      equicaloric 149 g CHO-29 g MCT suspension (CHO+MCT trial), 214 g CHO [high CHO 
      (HCHO)]-29 g MCT suspension (HCHO+MCT trial) or 29 g MCT solution (MCT trial). 
      Exogenous MCT oxidation was measured by adding a [1,1,1-13C]trioctanoate tracer 
      to the MCT oil. 13CO2 enrichment of breath samples were measured every 15 min. 
      During the second hour (60- to 120-min period), the amount of MCT oxidized was 
      72% of the amount ingested during the CHO+MCT trial, whereas during the MCT trial 
      only 33% was oxidized. The rate of MCT oxidation increased more rapidly during 
      the HCHO+MCT and CHO+MCT trials compared with the MCT trial, yet in all three 
      cases the oxidation rate stabilized at 0.12 g/min during 120-180 min of exercise. 
      It is concluded that more MCTs are oxidized when ingested in combination with 
      CHOs. Data do confirm the hypothesis that oral MCTs might serve as an energy 
      source in addition to glucose during exercise because the metabolic availability 
      of MCTs was high during the last hour of exercise, with oxidation rates being 
      approximately 70% of the ingestion rate.(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Jeukendrup, A E
AU  - Jeukendrup AE
AD  - Department of Human Biology, University of Limburg, Maastricht, The Netherlands.
FAU - Saris, W H
AU  - Saris WH
FAU - Schrauwen, P
AU  - Schrauwen P
FAU - Brouns, F
AU  - Brouns F
FAU - Wagenmakers, A J
AU  - Wagenmakers AJ
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Appl Physiol (1985)
JT  - Journal of applied physiology (Bethesda, Md. : 1985)
JID - 8502536
RN  - 0 (Blood Glucose)
RN  - 0 (Carbon Isotopes)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Fatty Acids, Nonesterified)
RN  - 0 (Lactates)
RN  - 0 (Triglycerides)
RN  - 33X04XA5AT (Lactic Acid)
SB  - IM
MH  - Adult
MH  - Blood Glucose/metabolism
MH  - Carbon Isotopes
MH  - Cross-Over Studies
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Double-Blind Method
MH  - Exercise/*physiology
MH  - Fatty Acids, Nonesterified/blood
MH  - Humans
MH  - Lactates/blood
MH  - Lactic Acid
MH  - Male
MH  - Oxidation-Reduction
MH  - Triglycerides/*metabolism
EDAT- 1995/09/01 00:00
MHDA- 1995/09/01 00:01
CRDT- 1995/09/01 00:00
PHST- 1995/09/01 00:00 [pubmed]
PHST- 1995/09/01 00:01 [medline]
PHST- 1995/09/01 00:00 [entrez]
AID - 10.1152/jappl.1995.79.3.756 [doi]
PST - ppublish
SO  - J Appl Physiol (1985). 1995 Sep;79(3):756-62. doi: 10.1152/jappl.1995.79.3.756.