PMID- 8575781
OWN - NLM
STAT- MEDLINE
DCOM- 19960314
LR  - 20071114
IS  - 0888-7543 (Print)
IS  - 0888-7543 (Linking)
VI  - 29
IP  - 3
DP  - 1995 Oct 10
TI  - Head to tail organization of the human COL6A1 and COL6A2 genes by fiber-FISH.
PG  - 801-3
AB  - Two type VI collagen genes, COL6A1 and COL6A2, both map to 21q22.3, but the 
      order, distance, and organization of these two genes relative to one another were 
      not known. Recently developed high-resolution fluorescence in situ hybridization 
      (FISH) techniques have great potential to facilitate the construction of 
      fine-resolution maps of telomeric regions where gene density is high. Here we 
      have determined the distance separating the COL6A1 and COL6A2 genes (150 kb), the 
      size of the COL6A1 gene (29 kb); and the 5'-3' orientation of these genes (5' 
      COL6A1 3'-5' COL6A2 3') using fiber-FISH.
FAU - Heiskanen, M
AU  - Heiskanen M
AD  - Department of Clinical Chemistry, University of Helsinki, Finland.
FAU - Saitta, B
AU  - Saitta B
FAU - Palotie, A
AU  - Palotie A
FAU - Chu, M L
AU  - Chu ML
LA  - eng
GR  - AR 38912/AR/NIAMS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Genomics
JT  - Genomics
JID - 8800135
RN  - 9007-34-5 (Collagen)
SB  - IM
MH  - Chromosome Mapping
MH  - *Chromosomes, Human, Pair 21
MH  - Cloning, Molecular
MH  - Collagen/*genetics
MH  - Cosmids
MH  - Humans
MH  - In Situ Hybridization, Fluorescence/methods
MH  - Multigene Family
MH  - Telomere
EDAT- 1995/10/10 00:00
MHDA- 1995/10/10 00:01
CRDT- 1995/10/10 00:00
PHST- 1995/10/10 00:00 [pubmed]
PHST- 1995/10/10 00:01 [medline]
PHST- 1995/10/10 00:00 [entrez]
AID - S0888-7543(85)79008-8 [pii]
AID - 10.1006/geno.1995.9008 [doi]
PST - ppublish
SO  - Genomics. 1995 Oct 10;29(3):801-3. doi: 10.1006/geno.1995.9008.