PMID- 8577852
OWN - NLM
STAT- MEDLINE
DCOM- 19960312
LR  - 20061115
IS  - 0962-8436 (Print)
IS  - 0962-8436 (Linking)
VI  - 350
IP  - 1331
DP  - 1995 Oct 30
TI  - Phytochrome signal-transduction: characterization of pathways and isolation of 
      mutants.
PG  - 67-74
AB  - The study of phytochrome signalling has yielded a wealth of data describing both 
      the perception of light by the receptor, and the terminal steps in 
      phytochrome-regulated gene expression by a number of transcription factors. We 
      are now focusing on establishing the intervening steps linking phytochrome 
      photoactivation to gene expression, and the regulation and interactions of these 
      signalling pathways. Recent work has utilized both a pharmacological approach in 
      phototrophic soybean suspension cultures and microinjection techniques in tomato 
      to establish three distinct phytochrome signal-transduction pathways: (i) a 
      calcium-dependent pathway that regulates the expression of genes encoding the 
      chlorophyll a/b binding protein (CAB) and other components of photosystem II; 
      (ii) a cGMP-dependent pathway that regulates the expression of the gene encoding 
      chalcone synthase (CHS) and the production of anthocyanin pigments; and (iii) a 
      pathway dependent upon both calcium and cGMP that regulates the expression of 
      genes encoding components of photosystem I and is necessary for the production of 
      mature chloroplasts. To study the components and the regulation of phytochrome 
      signal-transduction pathways, mutants with altered photomorphogenic responses 
      have been isolated by a number of laboratories. However, with several possible 
      exceptions, little real progress has been made towards the isolation of mutants 
      in positive regulatory elements of the phytochrome signal-transduction pathway. 
      We have characterized a novel phytochrome A (PhyA)-mediated far-red light (FR) 
      response in Arabidopsis seedlings which we are currently using to screen for 
      specific phyA signal-transduction mutants.
FAU - Barnes, S A
AU  - Barnes SA
AD  - Laboratory of Plant Molecular Biology, Rockefeller University, New York, New York 
      10021-6399, USA.
FAU - Quaggio, R B
AU  - Quaggio RB
FAU - Chua, N H
AU  - Chua NH
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - Philos Trans R Soc Lond B Biol Sci
JT  - Philosophical transactions of the Royal Society of London. Series B, Biological 
      sciences
JID - 7503623
RN  - 0 (Arabidopsis Proteins)
RN  - 0 (PHYA protein, Arabidopsis)
RN  - 0 (Phytochrome A)
RN  - 11121-56-5 (Phytochrome)
SB  - IM
MH  - Arabidopsis/genetics/metabolism
MH  - Arabidopsis Proteins
MH  - Gene Expression Regulation, Plant/physiology
MH  - Genes, Plant/physiology
MH  - Mutagenesis/physiology
MH  - Phytochrome/*genetics/metabolism
MH  - Phytochrome A
MH  - Signal Transduction/*physiology
RF  - 20
EDAT- 1995/10/30 00:00
MHDA- 1995/10/30 00:01
CRDT- 1995/10/30 00:00
PHST- 1995/10/30 00:00 [pubmed]
PHST- 1995/10/30 00:01 [medline]
PHST- 1995/10/30 00:00 [entrez]
AID - 10.1098/rstb.1995.0139 [doi]
PST - ppublish
SO  - Philos Trans R Soc Lond B Biol Sci. 1995 Oct 30;350(1331):67-74. doi: 
      10.1098/rstb.1995.0139.