PMID- 8583408
OWN - NLM
STAT- MEDLINE
DCOM- 19960321
LR  - 20190512
IS  - 0022-3751 (Print)
IS  - 1469-7793 (Electronic)
IS  - 0022-3751 (Linking)
VI  - 489 ( Pt 1)
IP  - Pt 1
DP  - 1995 Nov 15
TI  - Carbohydrate ingestion and glycogen utilization in different muscle fibre types 
      in man.
PG  - 243-50
AB  - 1. The effect of carbohydrate (CHO) ingestion on muscle glycogen utilization 
      during exercise was examined on seven male subjects completing two 60 min 
      treadmill runs at 70% maximum oxygen uptake (VO2,max), 1 week apart. On each 
      occasion the subjects consumed either water or a 5.5% CHO-electrolyte solution 
      immediately before and during exercise. Muscle samples were obtained from the 
      vastus lateralis by needle biopsy before and immediately after exercise. Venous 
      blood samples were also collected from an ante-cubital vein at rest and at 10, 
      20, 40 and 60 min into the run. 2. Higher blood glucose concentrations (P < 0.01) 
      were observed throughout the run during the CHO trial compared with the water 
      trial. Serum insulin concentration was only higher after 20 min of exercise (P < 
      0.01). 3. A 28% reduction in mixed glycogen utilization was observed as a result 
      of CHO ingestion when compared with water ingestion (108.7 +/- 16.3 vs. 150.9 +/- 
      19.9 mmol (kg dry matter)-1, respectively; P < 0.01). 4. The ingestion of the CHO 
      solution resulted in sparing of glycogen in type I (slow twitch) fibres only (38 
      +/- 7% degradation of glycogen as opposed to 66 +/- 3% during the water trial; P 
      = 0.01).
FAU - Tsintzas, O K
AU  - Tsintzas OK
AD  - Department of Physical Education, Sports Science and Recreation Management, 
      Loughborough University, Leicsestershire, UK.
FAU - Williams, C
AU  - Williams C
FAU - Boobis, L
AU  - Boobis L
FAU - Greenhaff, P
AU  - Greenhaff P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Physiol
JT  - The Journal of physiology
JID - 0266262
RN  - 0 (Blood Glucose)
RN  - 0 (Carbohydrates)
RN  - 9005-79-2 (Glycogen)
SB  - IM
MH  - Adult
MH  - Blood Glucose/metabolism
MH  - Carbohydrates/*pharmacology
MH  - Exercise/*physiology
MH  - Glycogen/*metabolism
MH  - Humans
MH  - Male
MH  - Muscle Fibers, Slow-Twitch/*metabolism
MH  - Muscles/metabolism
MH  - Time Factors
PMC - PMC1156808
EDAT- 1995/11/15 00:00
MHDA- 1995/11/15 00:01
PMCR- 1995/11/15
CRDT- 1995/11/15 00:00
PHST- 1995/11/15 00:00 [pubmed]
PHST- 1995/11/15 00:01 [medline]
PHST- 1995/11/15 00:00 [entrez]
PHST- 1995/11/15 00:00 [pmc-release]
AID - 10.1113/jphysiol.1995.sp021046 [doi]
PST - ppublish
SO  - J Physiol. 1995 Nov 15;489 ( Pt 1)(Pt 1):243-50. doi: 
      10.1113/jphysiol.1995.sp021046.