PMID- 8590438
OWN - NLM
STAT- MEDLINE
DCOM- 19960325
LR  - 20131121
IS  - 0305-7232 (Print)
IS  - 0305-7232 (Linking)
VI  - 15
IP  - 2
DP  - 1995 Nov
TI  - Presence of D-aspartate and D-glutamate in tumor proteins.
PG  - 79-82
AB  - Over 50 years ago Kogl and Erxleben reported that tumor proteins contain 
      appreciable amounts of D-amino acids. This postulate remained highly 
      controversial for several years, during which time several researchers either 
      supported or refuted the hypothesis. We have analyzed several sets of tumors and 
      normal control tissues for the presence of D-aspartate (D-Asp) and D-glutamate 
      (D-Glu). Most tumors contain less D-Asp than the control tissues, whereas nearly 
      half of the tumors contain 1.6 to 5.4 times more D-Glu than the controls. The 
      tumors averaged 0.72% D-Asp and 0.61% D-Glu compared to 0.94% D-Asp and 0.35% 
      D-Glu in the control tissues. However, within the limits of experimental error, 
      there is no significant difference in the level of these D-amino acids between 
      the tumors and normal tissues.
FAU - Fisher, G H
AU  - Fisher GH
AD  - Department of Chemistry, Barry University, Miami Shores, FL 33161, USA.
FAU - Torres, D
AU  - Torres D
FAU - Bruna, J
AU  - Bruna J
FAU - Cerwinski, S
AU  - Cerwinski S
FAU - Martin, T
AU  - Martin T
FAU - Bergljung, C
AU  - Bergljung C
FAU - Gruneiro, A
AU  - Gruneiro A
FAU - Chou, S J
AU  - Chou SJ
FAU - Man, E H
AU  - Man EH
FAU - Pappatheodorou, S
AU  - Pappatheodorou S
LA  - eng
PT  - Journal Article
PL  - England
TA  - Cancer Biochem Biophys
JT  - Cancer biochemistry biophysics
JID - 7506524
RN  - 0 (Neoplasm Proteins)
RN  - 30KYC7MIAI (Aspartic Acid)
RN  - 3KX376GY7L (Glutamic Acid)
SB  - IM
MH  - Aspartic Acid/*analysis
MH  - Glutamic Acid/*analysis
MH  - Humans
MH  - Neoplasm Proteins/*chemistry
MH  - Neoplasms/chemistry
MH  - Stereoisomerism
EDAT- 1995/11/01 00:00
MHDA- 1995/11/01 00:01
CRDT- 1995/11/01 00:00
PHST- 1995/11/01 00:00 [pubmed]
PHST- 1995/11/01 00:01 [medline]
PHST- 1995/11/01 00:00 [entrez]
PST - ppublish
SO  - Cancer Biochem Biophys. 1995 Nov;15(2):79-82.