PMID- 8595371
OWN - NLM
STAT- MEDLINE
DCOM- 19960416
LR  - 20111117
IS  - 0145-5680 (Print)
IS  - 0145-5680 (Linking)
VI  - 41
IP  - 7
DP  - 1995 Nov
TI  - In situ hybridization of fluorescent probes on chromosomes, nuclei or stretched 
      DNA: applications in physical mapping and characterization of genomic 
      rearrangements.
PG  - 925-31
AB  - During the last few years, various technologies and applications of fluorescence 
      in situ hybridization (FISH) have been developed. Hybridization on nuclei allows 
      an increase in the resolution of the technique. It also permits the 
      characterization of some chromosomal abnormalities such as trisomies, monosomies 
      or translocations in pathological cells when it is difficult to obtain 
      metaphases. Recently, several methods which extend the chromatin or the DNA 
      molecules have been developed. Such a support increases the FISH resolution to 
      the molecular level.
FAU - Desmaze, C
AU  - Desmaze C
AD  - INSERM U434, Institut Curie, Laboratorie de Genetique des Tumeurs, Paris, France.
FAU - Aurias, A
AU  - Aurias A
LA  - eng
PT  - Journal Article
PL  - France
TA  - Cell Mol Biol (Noisy-le-grand)
JT  - Cellular and molecular biology (Noisy-le-Grand, France)
JID - 9216789
RN  - 0 (Molecular Probes)
RN  - 9007-49-2 (DNA)
SB  - IM
MH  - Cell Line
MH  - Cell Nucleus/ultrastructure
MH  - Chromosome Aberrations/genetics
MH  - Chromosome Deletion
MH  - Chromosome Mapping/methods
MH  - Chromosomes, Human/genetics
MH  - Chromosomes, Human, Pair 11/genetics
MH  - Chromosomes, Human, Pair 22/genetics
MH  - Cosmids
MH  - DNA/genetics
MH  - DiGeorge Syndrome/genetics
MH  - Gene Rearrangement
MH  - Humans
MH  - In Situ Hybridization, Fluorescence/*methods
MH  - Lymphocytes/ultrastructure
MH  - *Molecular Probes
MH  - Sarcoma, Ewing/genetics
MH  - Translocation, Genetic
EDAT- 1995/11/01 00:00
MHDA- 1995/11/01 00:01
CRDT- 1995/11/01 00:00
PHST- 1995/11/01 00:00 [pubmed]
PHST- 1995/11/01 00:01 [medline]
PHST- 1995/11/01 00:00 [entrez]
PST - ppublish
SO  - Cell Mol Biol (Noisy-le-grand). 1995 Nov;41(7):925-31.