PMID- 8597638 OWN - NLM STAT- MEDLINE DCOM- 19960423 LR - 20190905 IS - 0938-8990 (Print) IS - 0938-8990 (Linking) VI - 6 IP - 11 DP - 1995 Nov TI - Refined mapping of caltractin in human Xq28 and in the homologous region of the mouse X chromosome places the gene within the bare patches (Bpa) and striated (Str) critical regions. PG - 802-4 AB - Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. A human caltractin cDNA (CALT) has recently been mapped by fluorescence in situ hybridization (FISH) to Xq28. We report here refined mapping of the human CALT gene and its murine homolog between the loci DXS1104 (DXHXS1104) DXS52 (DXHXS52) by PCR and Southern analysis on YACs and somatic cell hybrids from the region in both species. These mapping studies place the gene within the critical region for the murine X-linked dominant, male lethal mutations bare batches and striated. FAU - Chatterjee, A AU - Chatterjee A AD - Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA. FAU - Tanaka, T AU - Tanaka T FAU - Parrish, J E AU - Parrish JE FAU - Herman, G E AU - Herman GE LA - eng GR - HG00131/HG/NHGRI NIH HHS/United States GR - R01 AR39499/AR/NIAMS NIH HHS/United States PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - Mamm Genome JT - Mammalian genome : official journal of the International Mammalian Genome Society JID - 9100916 RN - 0 (Calcium-Binding Proteins) RN - 0 (Chromosomal Proteins, Non-Histone) RN - 118216-31-2 (caltractin) SB - IM MH - Animals MH - Base Sequence MH - Blotting, Southern MH - Calcium-Binding Proteins/*genetics MH - *Chromosomal Proteins, Non-Histone MH - Chromosome Mapping/*methods MH - Chromosomes, Artificial, Yeast MH - Humans MH - Hybrid Cells MH - Mice MH - Molecular Sequence Data MH - Mutation MH - *X Chromosome EDAT- 1995/11/01 00:00 MHDA- 1995/11/01 00:01 CRDT- 1995/11/01 00:00 PHST- 1995/11/01 00:00 [pubmed] PHST- 1995/11/01 00:01 [medline] PHST- 1995/11/01 00:00 [entrez] AID - 10.1007/BF00539008 [doi] PST - ppublish SO - Mamm Genome. 1995 Nov;6(11):802-4. doi: 10.1007/BF00539008.