PMID- 8606112
OWN - NLM
STAT- MEDLINE
DCOM- 19960523
LR  - 20210526
IS  - 0019-9567 (Print)
IS  - 1098-5522 (Electronic)
IS  - 0019-9567 (Linking)
VI  - 64
IP  - 4
DP  - 1996 Apr
TI  - Immunoglobulin E elevation in Plasmodium chabaudi malaria.
PG  - 1432-3
AB  - In order to investigate the mechanism of immunoglobulin E (IgE) elevation in 
      malaria we studies mice infected with asexual blood stages of the rodent malaria 
      parasite Plasmodium chabaudi chabaudi for total IgE and IgE antimalarial 
      antibodies. Multiply infected mice had elevated levels of total as well as 
      malaria-specific IgE in their sera. Sera taken from mice 3 weeks after one 
      infection with P. chabaudi showed no IgE elevation, indicated that prolonged or 
      repeated exposure to the parasite is necessary for the induction of an IgE 
      response, which also is induced independently of previous or simultaneous 
      infection with other pathogens such as helminths.
FAU - Helmby, H
AU  - Helmby H
AD  - Department of Immunology, Stockholm University, Sweden.
FAU - Perlmann, H
AU  - Perlmann H
FAU - Troye-Blomberg, M
AU  - Troye-Blomberg M
FAU - Perlmann, P
AU  - Perlmann P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Infect Immun
JT  - Infection and immunity
JID - 0246127
RN  - 0 (Antibodies, Protozoan)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Animals
MH  - Antibodies, Protozoan/*biosynthesis
MH  - Female
MH  - Immunoglobulin E/*biosynthesis
MH  - Malaria/*immunology
MH  - Male
MH  - Mice
MH  - Mice, Inbred BALB C
MH  - Plasmodium chabaudi/*immunology
PMC - PMC173937
EDAT- 1996/04/01 00:00
MHDA- 1996/04/01 00:01
PMCR- 1996/04/01
CRDT- 1996/04/01 00:00
PHST- 1996/04/01 00:00 [pubmed]
PHST- 1996/04/01 00:01 [medline]
PHST- 1996/04/01 00:00 [entrez]
PHST- 1996/04/01 00:00 [pmc-release]
AID - 10.1128/iai.64.4.1432-1433.1996 [doi]
PST - ppublish
SO  - Infect Immun. 1996 Apr;64(4):1432-3. doi: 10.1128/iai.64.4.1432-1433.1996.