PMID- 8614315
OWN - NLM
STAT- MEDLINE
DCOM- 19960531
LR  - 20151119
IS  - 0195-9131 (Print)
IS  - 0195-9131 (Linking)
VI  - 27
IP  - 12
DP  - 1995 Dec
TI  - Effects of carbohydrate type and concentration and solution osmolality on water 
      absorption.
PG  - 1607-15
AB  - We studied intestinal absorption of solutions containing either one (glucose, 
      Glu, or maltodextrin, Mal) or two (fructose, Fru, and Glu or sucrose, Suc) 
      transportable carbohydrate (CHO) substrates using segmental perfusion technique 
      in eight healthy male subjects. These CHO were either free or directly 
      transportable monosaccharides (Glu, Fru), bound as the disaccharide (sucrose, 
      Suc), or as oligomers (maltodextrins, Mal). [CHO] was varied from 6% to 8% 
      (120-444 mmol.1(-1)). All solutions contained low [Na+] (15-19 mEq) and [K+] (3-4 
      mEq). Solutions osmolalities varied from 165 to 477 mOsm.kg(-1). Osmolalities in 
      the test segment ranged from 268 to 314 mOsm.kg(-1). The regression line of 
      osmolality with water absorption differed for single as compared with multiple 
      substrate solutions. The significantly different intercepts of these two 
      regression lines suggest that solutions with multiple substrates produce greater 
      water absorption at a given osmolality than those with one. Comparing all 
      solutions, test segment solute flux (partial r = 0.69) was more important than 
      mean osmolality (partial r = 0.32). In conclusion, solutions with multiple 
      substrates stimulate several different solute absorption mechanisms yielding 
      greater water absorption than solutions with only one substrate.
FAU - Shi, X
AU  - Shi X
AD  - Department of Exercise Science, University of Iowa, Iowa City 52242, USA.
FAU - Summers, R W
AU  - Summers RW
FAU - Schedl, H P
AU  - Schedl HP
FAU - Flanagan, S W
AU  - Flanagan SW
FAU - Chang, R
AU  - Chang R
FAU - Gisolfi, C V
AU  - Gisolfi CV
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Med Sci Sports Exerc
JT  - Medicine and science in sports and exercise
JID - 8005433
RN  - 0 (Amino Acids)
RN  - 0 (Carbohydrates)
RN  - 0 (Hypertonic Solutions)
RN  - 0 (Hypotonic Solutions)
RN  - 0 (Isotonic Solutions)
RN  - 0 (Polysaccharides)
RN  - 059QF0KO0R (Water)
RN  - 30237-26-4 (Fructose)
RN  - 57-50-1 (Sucrose)
RN  - 69-79-4 (Maltose)
RN  - 7CVR7L4A2D (maltodextrin)
RN  - 9NEZ333N27 (Sodium)
RN  - IY9XDZ35W2 (Glucose)
RN  - RWP5GA015D (Potassium)
SB  - IM
MH  - Amino Acids/administration & dosage/pharmacology
MH  - Analysis of Variance
MH  - Carbohydrates/administration & 
      dosage/classification/pharmacokinetics/*pharmacology
MH  - Fructose/administration & dosage/pharmacokinetics/pharmacology
MH  - Glucose/administration & dosage/pharmacokinetics/pharmacology
MH  - Humans
MH  - Hypertonic Solutions
MH  - Hypotonic Solutions
MH  - *Intestinal Absorption/drug effects
MH  - Isotonic Solutions
MH  - Male
MH  - Maltose/administration & dosage/pharmacokinetics/pharmacology
MH  - Osmolar Concentration
MH  - Polysaccharides/administration & dosage/pharmacokinetics/pharmacology
MH  - Potassium/administration & dosage
MH  - Regression Analysis
MH  - Sodium/administration & dosage
MH  - Sucrose/administration & dosage/pharmacokinetics/pharmacology
MH  - Water/*metabolism
EDAT- 1995/12/01 00:00
MHDA- 1995/12/01 00:01
CRDT- 1995/12/01 00:00
PHST- 1995/12/01 00:00 [pubmed]
PHST- 1995/12/01 00:01 [medline]
PHST- 1995/12/01 00:00 [entrez]
PST - ppublish
SO  - Med Sci Sports Exerc. 1995 Dec;27(12):1607-15.