PMID- 8616021
OWN - NLM
STAT- MEDLINE
DCOM- 19960610
LR  - 20190705
IS  - 0007-1048 (Print)
IS  - 0007-1048 (Linking)
VI  - 92
IP  - 3
DP  - 1996 Mar
TI  - Atypical chronic myeloid leukaemia, a distinct clinical entity related to the 
      myelodysplastic syndrome?
PG  - 582-6
AB  - The FAB group has recently published guidelines for distinguishing chronic 
      granulocytic leukaemia (CGL) from chronic myelomonocytic leukaemia (CMML) and 
      atypical chronic myeloid leukaemia (aCML). Whereas CGL is generally recognized to 
      be a distinct entity, there is debate as to whether CMML and aCML are separate 
      disorders or part of a spectrum of myeloproliferative disorders with dysplastic 
      features. Data are presented on 10 cases who developed features of a CML during 
      the course of their disease but who presented with a normal or a low leucocyte 
      count without a monocytosis and were diagnosed as refractory anaemia. This 
      suggests that, at least in some cases, aCML represents an unusual evolution of 
      MDS, and even though these patients have a uniformly poor prognosis it may be 
      premature to regard aCML as a distinct clinical entity.
FAU - Oscier, D G
AU  - Oscier DG
AD  - Department of Haematology, Royal Bournemouth Hospital.
LA  - eng
PT  - Journal Article
PL  - England
TA  - Br J Haematol
JT  - British journal of haematology
JID - 0372544
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - Humans
MH  - Karyotyping
MH  - Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*diagnosis/mortality
MH  - Leukocyte Count
MH  - Male
MH  - Middle Aged
MH  - Myelodysplastic Syndromes/*diagnosis/mortality
EDAT- 1996/03/01 00:00
MHDA- 1996/03/01 00:01
CRDT- 1996/03/01 00:00
PHST- 1996/03/01 00:00 [pubmed]
PHST- 1996/03/01 00:01 [medline]
PHST- 1996/03/01 00:00 [entrez]
AID - 10.1046/j.1365-2141.1996.396933.x [doi]
PST - ppublish
SO  - Br J Haematol. 1996 Mar;92(3):582-6. doi: 10.1046/j.1365-2141.1996.396933.x.