PMID- 8618628
OWN - NLM
STAT- MEDLINE
DCOM- 19960613
LR  - 20061115
IS  - 0028-2162 (Print)
IS  - 0028-2162 (Linking)
VI  - 140
IP  - 3
DP  - 1996 Jan 20
TI  - [Human herpes viruses type 6 and 7; causative agents of, among others, exanthema 
      subitum].
PG  - 124-8
AB  - A serendipitous discovery during early AIDS investigations was human herpes virus 
      type 6 (HHV-6). Two years later (1988) it was shown that HHV-6 and later on also 
      HHV-7 are the causes of exanthema subitum, a childhood disease with previously 
      unknown causation. HHV-6 and HHV-7 are the main cause of febrile seizures. It is 
      assumed that 90% of children are infected before they are three years old. The 
      viruses are also found in adults; HHV-6 may cause mononucleosis and hepatitis. 
      HHV-6 and HHV-7 infect CD4+ cells and may influence the course of HIV infection. 
      In AIDS patients HHV-6 and cytomegalovirus are often isolated together from the 
      lungs, possibly because they activate each other. Another possibility is that the 
      circumstances in the lungs are favourable to both. HHV-6 and HHV-7 infection may 
      be serologically diagnosed. There is little experience with antiviral treatment.
FAU - Galama, J M
AU  - Galama JM
AD  - Academisch Ziekenhuis, afd. Medische Microbiologie, Nijmegen.
LA  - dut
PT  - English Abstract
PT  - Journal Article
PT  - Review
TT  - Humane herpesvirussen type 6 en 7; verwekkers van onder meer exanthema subitum.
PL  - Netherlands
TA  - Ned Tijdschr Geneeskd
JT  - Nederlands tijdschrift voor geneeskunde
JID - 0400770
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Child
MH  - Child, Preschool
MH  - Exanthema Subitum/*virology
MH  - Herpesviridae Infections/diagnosis/transmission/*virology
MH  - Herpesvirus 6, Human/*isolation & purification
MH  - Herpesvirus 7, Human/*isolation & purification
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Middle Aged
MH  - Prevalence
RF  - 20
EDAT- 1996/01/20 00:00
MHDA- 1996/01/20 00:01
CRDT- 1996/01/20 00:00
PHST- 1996/01/20 00:00 [pubmed]
PHST- 1996/01/20 00:01 [medline]
PHST- 1996/01/20 00:00 [entrez]
PST - ppublish
SO  - Ned Tijdschr Geneeskd. 1996 Jan 20;140(3):124-8.