PMID- 8619978 OWN - NLM STAT- MEDLINE DCOM- 19960620 LR - 20131121 IS - 1053-4628 (Print) IS - 1053-4628 (Linking) VI - 20 IP - 2 DP - 1996 Winter TI - Teething and acute graft vs. host disease: a clinical observation. PG - 159-60 AB - A 5-month-old girl, treated with bone marrow transplantation for severe combined immunodeficiency, developed two episodes of severe acute graft vs. host disease (GVHD) while teething. A dramatic improvement in GVHD was noted after the completion of tooth eruption. It is suggested that the release of interleukin-1, associated with the traumatized gingival tissue, is the triggering mediator for the GVHD. FAU - Shapira, J AU - Shapira J AD - Department of Pediatric Dentistry, Hadassah Faculty of Dental Medicine, Jerusalem, Israel. FAU - Aker, M AU - Aker M FAU - Nagler, A AU - Nagler A FAU - Or, R AU - Or R FAU - Kapelushnik, J AU - Kapelushnik J LA - eng PT - Case Reports PT - Journal Article PL - Singapore TA - J Clin Pediatr Dent JT - The Journal of clinical pediatric dentistry JID - 9100079 RN - 0 (Immunosuppressive Agents) RN - 0 (Interleukin-1) RN - 83HN0GTJ6D (Cyclosporine) MH - Acute Disease MH - Bone Marrow Transplantation MH - Cyclosporine/therapeutic use MH - Female MH - Gingiva/immunology/injuries/metabolism MH - Graft vs Host Disease/*etiology MH - Humans MH - Immunosuppressive Agents/therapeutic use MH - Infant MH - Interleukin-1/*biosynthesis MH - Severe Combined Immunodeficiency/therapy MH - Tooth Eruption/*immunology EDAT- 1996/01/01 00:00 MHDA- 1996/01/01 00:01 CRDT- 1996/01/01 00:00 PHST- 1996/01/01 00:00 [pubmed] PHST- 1996/01/01 00:01 [medline] PHST- 1996/01/01 00:00 [entrez] PST - ppublish SO - J Clin Pediatr Dent. 1996 Winter;20(2):159-60.