PMID- 8624656 OWN - NLM STAT- MEDLINE DCOM- 19960621 LR - 20100324 IS - 1076-0512 (Print) IS - 1076-0512 (Linking) VI - 22 IP - 4 DP - 1996 Apr TI - Photothermal sclerosis of leg veins. ESC Medical Systems, LTD Photoderm VL Cooperative Study Group. PG - 323-30 AB - BACKGROUND: The flashlamp-pumped pulse dye laser at 585 nm has previously been reported to be somewhat effective in treating leg telangiectasia with diameters less than 0.2 mm. A pulsed photothermal devise (intense pulsed light source [IPLS]) has been developed to treat leg veins ranging in size from 0.1 to 3 mm in diameter. Vessel necrosis occurs from an intense pulsed light that penetrates through the skin and is absorbed by the blood vessels based on the principle of selective photothermolysis. OBJECTIVE: To determine the effectiveness of this novel device on treating leg veins. METHODS: One hundred fifty-nine patients with 369 lesions were treated with the IPLS in a multicenter trial. RESULTS: Clearance of 75-100% was achieved in 79% of treated lesions. Better than 50% clearance was achieved in 94% of completed cases. A very low rate of adverse effects occurred. CONCLUSION: The IPLS is a safe and effective modality to treat leg veins ranging in size from 0.1 to 3 mm in diameter. FAU - Goldman, M P AU - Goldman MP AD - Dermatology Associates of San Diego County, Inc., California, La Jolla 92037, USA. FAU - Eckhouse, S AU - Eckhouse S LA - eng PT - Clinical Trial PT - Journal Article PT - Multicenter Study PL - United States TA - Dermatol Surg JT - Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] JID - 9504371 SB - IM CIN - Dermatol Surg. 1997 Apr;23(4):303-5. PMID: 9149798 MH - Adolescent MH - Adult MH - Aged MH - Female MH - Humans MH - *Light Coagulation/adverse effects/methods MH - Male MH - Middle Aged MH - Pigmentation Disorders/etiology MH - Prospective Studies MH - Purpura/etiology MH - Telangiectasis/surgery MH - Varicose Veins/*surgery EDAT- 1996/04/01 00:00 MHDA- 1996/04/01 00:01 CRDT- 1996/04/01 00:00 PHST- 1996/04/01 00:00 [pubmed] PHST- 1996/04/01 00:01 [medline] PHST- 1996/04/01 00:00 [entrez] AID - 1076051295000275 [pii] PST - ppublish SO - Dermatol Surg. 1996 Apr;22(4):323-30.