PMID- 8644541
OWN - NLM
STAT- MEDLINE
DCOM- 19960712
LR  - 20151008
IS  - 0029-0203 (Print)
IS  - 0029-0203 (Linking)
VI  - 100
IP  - 4
DP  - 1996 Apr
TI  - [Anterior uveitis with ankylosing spondylitis and HLA].
PG  - 292-5
AB  - We investigated the relationship between anterior uveitis with ankylosing 
      spondylitis (AS) and human leukocyte antigen (HLA) alleles. Forty patients were 
      studied, 19 with anterior uveitis and 21 without it. No deviation in the 
      frequencies of HLA-B27 antigen and related alleles were observed between the two 
      groups of patients. Twelve cases (63.2%) with anterior uveitis had expressed 
      HLA-DR8 (DRB1 0803). On the other hand, only 1 case had expressed the same 
      antigen and this difference was statistically significant (relative risk: 34.3 Pc 
      < 0.007) as we reported previously. We found HLA-DR8 was a candidate for 
      susceptibility to anterior uveitis in AS.
FAU - Numaga, J
AU  - Numaga J
AD  - Department of Ophthalmology, University of Tokyo, School of Medicine, Japan.
FAU - Islam, M S
AU  - Islam MS
FAU - Mitsui, H
AU  - Mitsui H
FAU - Maeda, H
AU  - Maeda H
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Nippon Ganka Gakkai Zasshi
JT  - Nippon Ganka Gakkai zasshi
JID - 7505716
RN  - 0 (HLA Antigens)
RN  - 0 (HLA-DR Antigens)
RN  - 0 (HLA-DR Serological Subtypes)
RN  - 0 (HLA-DR8 antigen)
SB  - IM
MH  - Alleles
MH  - Base Sequence
MH  - HLA Antigens/chemistry/*genetics
MH  - HLA-DR Antigens/genetics
MH  - HLA-DR Serological Subtypes
MH  - Humans
MH  - Molecular Sequence Data
MH  - Polymerase Chain Reaction
MH  - Polymorphism, Single-Stranded Conformational
MH  - Spondylitis, Ankylosing/complications/*immunology
MH  - Uveitis, Anterior/complications/*immunology
EDAT- 1996/04/01 00:00
MHDA- 1996/04/01 00:01
CRDT- 1996/04/01 00:00
PHST- 1996/04/01 00:00 [pubmed]
PHST- 1996/04/01 00:01 [medline]
PHST- 1996/04/01 00:00 [entrez]
PST - ppublish
SO  - Nippon Ganka Gakkai Zasshi. 1996 Apr;100(4):292-5.