PMID- 8644592 OWN - NLM STAT- MEDLINE DCOM- 19960716 LR - 20190626 IS - 0002-8703 (Print) IS - 0002-8703 (Linking) VI - 131 IP - 6 DP - 1996 Jun TI - Electrocardiographic abnormalities in patients receiving hemodialysis. PG - 1137-44 AB - We assessed standard 12-lead and Holter electrocardiographic (ECG) abnormalities in maintenance hemodialysis (HD) patients. Of 221 outpatients receiving HD, 143 (65%) had ECG abnormalities. Rates were higher in male, elderly, hypertensive, and diabetic patients than in female, younger, normotensive, and nondiabetic patients. The prevalence of ECG changes correlated inversely with HD duration. Serial ECGs were compared in 87 patients whose average HD duration was 7.5 +/- 2.5 years. Thirty-four patients (39%) showed normal ECGs throughout, 27 (31%) relatively stable abnormalities, 22 (25%) worsening, and 4 (5%) reversion to normal. Age, hypertension, and diabetes are factors related to abnormal ECG findings. Among the 142 Holter recordings from 72 patients, 70 (97%) were basically in sinus rhythm, and 2 (3%) were in atrial fibrillation. The average frequency of supraventricular premature contractions (SVPCs) was 1597 +/- 9725 per 24 hours, and that of ventricular premature contractions (VPCs), 556 +/- 1415. VPCs were multifocal in 9%, in runs in 25%, and early in 1%. In 29 (40%) of recordings, VPCs appeared mainly during and for several hours after HD. ST-T changes were seen in 43 (60%). In 11, ST depression occurred during and a few hours after HD. Patients receiving HD showed diverse ECG abnormalities. Holter ECGs revealed a high incidence of arrhythmias and ST-T changes, which frequently appeared in relation to HD timing. FAU - Abe, S AU - Abe S AD - Department of Internal Medicine, Keio University, Tokyo, Japan. FAU - Yoshizawa, M AU - Yoshizawa M FAU - Nakanishi, N AU - Nakanishi N FAU - Yazawa, T AU - Yazawa T FAU - Yokota, K AU - Yokota K FAU - Honda, M AU - Honda M FAU - Sloman, G AU - Sloman G LA - eng PT - Journal Article PL - United States TA - Am Heart J JT - American heart journal JID - 0370465 SB - IM CIN - Am Heart J. 1997 Dec;134(6):1138-40. PMID: 9424077 MH - Adolescent MH - Adult MH - Age Factors MH - Aged MH - Arrhythmias, Cardiac/diagnosis/*etiology MH - Cardiac Complexes, Premature/etiology MH - Diabetes Complications MH - *Electrocardiography, Ambulatory MH - Female MH - Follow-Up Studies MH - Humans MH - Hypertension/complications MH - Kidney Failure, Chronic/therapy MH - Male MH - Middle Aged MH - Renal Dialysis/*adverse effects EDAT- 1996/06/01 00:00 MHDA- 1996/06/01 00:01 CRDT- 1996/06/01 00:00 PHST- 1996/06/01 00:00 [pubmed] PHST- 1996/06/01 00:01 [medline] PHST- 1996/06/01 00:00 [entrez] AID - S0002-8703(96)90088-5 [pii] AID - 10.1016/s0002-8703(96)90088-5 [doi] PST - ppublish SO - Am Heart J. 1996 Jun;131(6):1137-44. doi: 10.1016/s0002-8703(96)90088-5.