PMID- 8645854 OWN - NLM STAT- MEDLINE DCOM- 19960725 LR - 20190512 IS - 1058-4838 (Print) IS - 1058-4838 (Linking) VI - 21 IP - 4 DP - 1995 Oct TI - Development of human T-cell lymphotropic virus type I-associated adult T-cell leukemia/lymphoma during immunosuppressive treatment following renal transplantation. PG - 992-3 AB - Although it is recognized that there is an increased incidence of lymphoproliferative disorders among patients who have received immunosuppressive therapy following transportation, there have been few reports of adult T-cell leukemia/lymphoma (ATLL) developing in previously asymptomatic carriers of human T-cell lymphotropic virus type I (HTLV-I) who have undergone transplantation. We describe the development of such a tumor in a man who was HTLV-I-positive and received immunosuppressive treatment following renal transplantation. As the number of individuals in ethnic groups at risk for organ transplantation increases, it would seem prudent to screen such individuals for carriage of HTLV-I before transplantation and to follow them prospectively to confirm if transplantation and immunosuppression predispose to the development of ATLL. FAU - Jenks, P J AU - Jenks PJ AD - Department of Virology, Royal Hospitals NHS Trust, London, United Kingdom. FAU - Barrett, W Y AU - Barrett WY FAU - Raftery, M J AU - Raftery MJ FAU - Kelsey, S M AU - Kelsey SM FAU - van der Walt, J D AU - van der Walt JD FAU - Kon, S P AU - Kon SP FAU - Breuer, J AU - Breuer J LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Clin Infect Dis JT - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JID - 9203213 RN - 0 (DNA, Viral) RN - 0 (Immunosuppressive Agents) SB - IM MH - DNA, Viral/analysis MH - Fatal Outcome MH - Human T-lymphotropic virus 1/isolation & purification MH - Humans MH - Immunosuppressive Agents/administration & dosage/*adverse effects MH - Kidney Transplantation/*adverse effects/immunology MH - Leukemia-Lymphoma, Adult T-Cell/*etiology MH - Male MH - Middle Aged MH - Retrospective Studies EDAT- 1995/10/01 00:00 MHDA- 1995/10/01 00:01 CRDT- 1995/10/01 00:00 PHST- 1995/10/01 00:00 [pubmed] PHST- 1995/10/01 00:01 [medline] PHST- 1995/10/01 00:00 [entrez] AID - 10.1093/clinids/21.4.992 [doi] PST - ppublish SO - Clin Infect Dis. 1995 Oct;21(4):992-3. doi: 10.1093/clinids/21.4.992.