PMID- 8646330
OWN - NLM
STAT- MEDLINE
DCOM- 19960725
LR  - 20190720
IS  - 0021-9673 (Print)
IS  - 0021-9673 (Linking)
VI  - 731
IP  - 1-2
DP  - 1996 Apr 19
TI  - Solid-phase extraction for the selective isolation of polycyclic aromatic 
      hydrocarbons, azaarenes and heterocyclic aromatic amines in charcoal-grilled 
      meat.
PG  - 85-94
AB  - A method for the simultaneous analysis of 12 mutagenic and/or carcinogenic 
      compounds is described; these substances belong to three different chemical 
      groups: polycyclic aromatic hydrocarbons (PAHs), azaarenes, i.e., 
      nitrogen-containing polycyclic aromatic hydrocarbons (PANHs), and heterocyclic 
      aromatic amines (HAAs). The selective enrichment procedure includes coupling of 
      solid-phase extraction (SPE) steps using diatomaceous earth, propylsulfonic acid, 
      silica gel and octadecylsilane columns. The eluted fractions were analysed by 
      high-performance liquid chromatography with UV and electrochemical detection. 
      Levels measured were estimated to be 4-19 ng g-1. Peak confirmation was carried 
      out by GC-MS for both PAHs and PANHs, and by LC with a photodiode array detector 
      for HAAs. The method was applied to the analysis of charcoal-grilled meat and was 
      judged to be generally applicable for detection of these mutagens at the ppb 
      level in processed foods.
FAU - Rivera, L
AU  - Rivera L
AD  - Departament de Quimica Analitica, Universitat de Barcelona, Spain.
FAU - Curto, M J
AU  - Curto MJ
FAU - Pais, P
AU  - Pais P
FAU - Galceran, M T
AU  - Galceran MT
FAU - Puignou, L
AU  - Puignou L
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Amines)
RN  - 0 (Aza Compounds)
RN  - 0 (Carcinogens)
RN  - 0 (Heterocyclic Compounds)
RN  - 0 (Mutagens)
RN  - 0 (Polycyclic Compounds)
RN  - 16291-96-6 (Charcoal)
SB  - IM
MH  - Amines/analysis/isolation & purification
MH  - Aza Compounds/analysis/*isolation & purification
MH  - Carcinogens/analysis/isolation & purification
MH  - Charcoal
MH  - Chromatography, High Pressure Liquid
MH  - Cooking
MH  - Gas Chromatography-Mass Spectrometry
MH  - Heterocyclic Compounds/analysis/*isolation & purification
MH  - Meat/*analysis
MH  - Mutagens/analysis/isolation & purification
MH  - Polycyclic Compounds/analysis/*isolation & purification
MH  - Spectrophotometry, Ultraviolet
EDAT- 1996/04/19 00:00
MHDA- 1996/04/19 00:01
CRDT- 1996/04/19 00:00
PHST- 1996/04/19 00:00 [pubmed]
PHST- 1996/04/19 00:01 [medline]
PHST- 1996/04/19 00:00 [entrez]
AID - 0021-9673(95)01224-9 [pii]
AID - 10.1016/0021-9673(95)01224-9 [doi]
PST - ppublish
SO  - J Chromatogr A. 1996 Apr 19;731(1-2):85-94. doi: 10.1016/0021-9673(95)01224-9.