PMID- 8668853 OWN - NLM STAT- MEDLINE DCOM- 19960806 LR - 20211203 IS - 0882-0546 (Print) IS - 0882-0546 (Linking) VI - 10 IP - 4 DP - 1995 Dec TI - Human herpesvirus 6 as a possible cause of pneumonia. PG - 254-8 AB - Case reports and limited retrospective studies have established that human herpesvirus 6 (HHV-6) can be found in lung tissues from patients with pneumonia. Most cases of HHV-6-associated pneumonia involve immunocompromised patients, especially those who have received a bone marrow transplant or who have been infected by the human immunodeficiency virus. Additional data suggest that HHV-6 commonly reactivates in immunosuppressed individuals. The virus has been identified in a variety of organ systems, including the respiratory tract, without associated pathology. A better understanding of HHV-6 pathogenesis is needed before rational clinical intervention for HHV-6-associated pneumonias can be implemented. FAU - Cone, R W AU - Cone RW AD - Department of Medicine, University Hospital, Zurich, Switzerland. LA - eng PT - Journal Article PT - Review PL - United States TA - Semin Respir Infect JT - Seminars in respiratory infections JID - 8700961 SB - IM MH - Bone Marrow Transplantation/adverse effects MH - Child, Preschool MH - HIV Infections/complications MH - Herpesvirus 6, Human/isolation & purification/*pathogenicity MH - Humans MH - *Immunocompromised Host MH - Immunosuppression Therapy/adverse effects MH - Infant MH - Infant, Newborn MH - Pneumonia, Viral/diagnosis/*virology RF - 32 EDAT- 1995/12/01 00:00 MHDA- 1995/12/01 00:01 CRDT- 1995/12/01 00:00 PHST- 1995/12/01 00:00 [pubmed] PHST- 1995/12/01 00:01 [medline] PHST- 1995/12/01 00:00 [entrez] PST - ppublish SO - Semin Respir Infect. 1995 Dec;10(4):254-8.