PMID- 8677720
OWN - NLM
STAT- MEDLINE
DCOM- 19960809
LR  - 20161123
IS  - 1997-7298 (Print)
IS  - 1997-7298 (Linking)
VI  - 96
IP  - 1
DP  - 1996
TI  - [A disorder of serotonin metabolism in patients in the acute period of 
      nontraumatic intracranial hemorrhages].
PG  - 50-2
AB  - The indices of serotonin metabolism in cerebrospinal fluid (CSF) and blood were 
      studied in 43 patients with nontraumatic intracerebral hemorrhage in the interval 
      from 1 - 2 to 28 days after the onset of the disease. The considerable increase 
      of tryptophan, serotonin and its main metabolite 5-hydroxyindoleacetic acid 
      (5-HAA) in CSF and blood was found. The relationship between liquor and blood 
      serum serotonin levels, hemorrhage focus size, severity and outcome of disease 
      was also observed. There were no significant differences between serotonin, 
      5-HAA, free and bound serotonin levels in patients with the break of blood into 
      different part of liquor space. The possible mechanisms of alteration of 
      serotonin metabolism in patients with intracerebral hemorrhage were discussed.
FAU - Lebedeva, N V
AU  - Lebedeva NV
FAU - Khrapova, E V
AU  - Khrapova EV
FAU - Kugoev, A I
AU  - Kugoev AI
FAU - Solomonov, A P
AU  - Solomonov AP
LA  - rus
PT  - Comparative Study
PT  - Journal Article
TT  - Narushenie obmena serotonina u bol'nykh v ostrom periode netravmaticheskikh 
      vnutrimozgovykh krovoizliianii.
PL  - Russia (Federation)
TA  - Zh Nevrol Psikhiatr Im S S Korsakova
JT  - Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
JID - 9712194
RN  - 333DO1RDJY (Serotonin)
RN  - 54-16-0 (Hydroxyindoleacetic Acid)
RN  - 8DUH1N11BX (Tryptophan)
SB  - IM
MH  - Acute Disease
MH  - Adult
MH  - Aged
MH  - Brain/diagnostic imaging
MH  - Cerebral Hemorrhage/diagnostic imaging/*metabolism
MH  - Female
MH  - Humans
MH  - Hydroxyindoleacetic Acid/analysis/metabolism
MH  - Male
MH  - Middle Aged
MH  - Serotonin/analysis/*metabolism
MH  - Time Factors
MH  - Tomography, X-Ray Computed
MH  - Tryptophan/analysis/metabolism
EDAT- 1996/01/01 00:00
MHDA- 1996/01/01 00:01
CRDT- 1996/01/01 00:00
PHST- 1996/01/01 00:00 [pubmed]
PHST- 1996/01/01 00:01 [medline]
PHST- 1996/01/01 00:00 [entrez]
PST - ppublish
SO  - Zh Nevrol Psikhiatr Im S S Korsakova. 1996;96(1):50-2.