PMID- 8682500
OWN - NLM
STAT- MEDLINE
DCOM- 19960820
LR  - 20190722
IS  - 0340-6717 (Print)
IS  - 0340-6717 (Linking)
VI  - 98
IP  - 1
DP  - 1996 Jul
TI  - Fine mapping of the 1q21 breakpoint of the papillary renal cell 
      carcinoma-associated (X;1) translocation.
PG  - 16-21
AB  - A combination of Southern blot analysis on a panel of tumor-derived somatic cell 
      hybrids and fluorescence in situ hybridization (FISH) techniques was used to map 
      a series of DNA markers relative to the 1q21 breakpoint of the renal cell 
      carcinoma (RCC)-associated (X;1)-(p11;q21) translocation. This breakpoint maps 
      between several members of the S100 family which are clustered in the 1q21 region 
      and a conserved region between man and mouse containing the markers 
      SPTA1-CRP-APCS-FcER1A-ATP1A2-APOA2. The location of the breakpoint coincides with 
      the transition of a region of synteny of human chromosome 1 with mouse 
      chromosomes 3 and 1.
FAU - Weterman, M A
AU  - Weterman MA
AD  - Department of Human Genetics, University Hospital Nijmegen, The Netherlands.
FAU - Wilbrink, M
AU  - Wilbrink M
FAU - Dijkhuizen, T
AU  - Dijkhuizen T
FAU - van den Berg, E
AU  - van den Berg E
FAU - Geurts van Kessel, A
AU  - Geurts van Kessel A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Hum Genet
JT  - Human genetics
JID - 7613873
RN  - 0 (DNA Probes)
RN  - 0 (Genetic Markers)
SB  - IM
MH  - Animals
MH  - Blotting, Southern
MH  - Carcinoma, Renal Cell/*genetics
MH  - *Chromosome Mapping
MH  - Chromosomes, Artificial, Yeast/genetics
MH  - Chromosomes, Human, Pair 1/*genetics
MH  - Cricetinae
MH  - DNA Probes
MH  - Genetic Markers/genetics
MH  - Humans
MH  - Hybrid Cells
MH  - In Situ Hybridization, Fluorescence
MH  - Kidney Neoplasms/*genetics
MH  - Translocation, Genetic/*genetics
MH  - Tumor Cells, Cultured
MH  - X Chromosome/*genetics
EDAT- 1996/07/01 00:00
MHDA- 1996/07/01 00:01
CRDT- 1996/07/01 00:00
PHST- 1996/07/01 00:00 [pubmed]
PHST- 1996/07/01 00:01 [medline]
PHST- 1996/07/01 00:00 [entrez]
AID - 10.1007/s004390050153 [doi]
PST - ppublish
SO  - Hum Genet. 1996 Jul;98(1):16-21. doi: 10.1007/s004390050153.