PMID- 8683431
OWN - NLM
STAT- MEDLINE
DCOM- 19960820
LR  - 20121115
IS  - 0914-5087 (Print)
IS  - 0914-5087 (Linking)
VI  - 27
IP  - 1
DP  - 1996 Jan
TI  - [Left cardiac output curve and pulmonary venous return curve in patients with 
      various heart diseases].
PG  - 21-7
AB  - This study assessed the cardiac function of humans by drawing simultaneous left 
      cardiac output and pulmonary venous return curves using radionuclide 
      angiocardiography and right heart catheterization which allows recording of the 
      pressure-flow relationship. Thirty-one subjects with various cardiac diseases 
      were divided into two groups [18 patients with New York Heart Association (NYHA) 
      functional class I and 13 patients with NYHA classes II or III]. Mean pulmonary 
      filling pressure (Pmp) was calculated from the formula of Guyton, using pulmonary 
      arterial compliance which was measured by Reuben's method and pulmonary venous 
      compliance measured as reported previously. On the pressure-flow plane, the down 
      slope of the pulmonary venous return curve was drawn by joining the points of 
      (Pmp, 0) and (mean pulmonary capillary wedge pressure, cardiac output). To 
      construct the cardiac output curve, two levels of lower body negative pressure 
      were used to regulate the venous return to the heart. Pmp and the resistance to 
      pulmonary venous return in NYHA II or III patients were significantly higher than 
      those in NYHA I patients (Pmp: 16.3 +/- 1.5 vs 9.0 +/- 0.5 mmHg, p < 0.01; 
      resistance to pulmonary venous return: 0.75 +/- 0.09 vs 0.43 +/- 0.04 mmHg/l/min, 
      p < 0.01, respectively). The slope of pulmonary venous return curve in NYHA II or 
      III patients was smaller than that in NYHA I patients and the pulmonary venous 
      return curve in NYHA II or III patients shifted rightward. The slope of cardiac 
      output curve in NYHA II or III patients was significantly smaller than that in 
      NYHA I patients. This curve in NYHA II or III patients shifted downward and 
      rightward. These results indicate that simultaneous cardiac output and pulmonary 
      venous return curves may be a useful method for assessing the cardiac function in 
      patients with various heart diseases.
FAU - Iida, M
AU  - Iida M
AD  - Second Department of Internal Medicine, Gifu University School of Medicine, 
      Japan.
FAU - Gotoh, K
AU  - Gotoh K
FAU - Yagi, Y
AU  - Yagi Y
FAU - Deguchi, F
AU  - Deguchi F
FAU - Terashima, Y
AU  - Terashima Y
FAU - Nagashima, K
AU  - Nagashima K
FAU - Nomura, M
AU  - Nomura M
FAU - Yasuda, N
AU  - Yasuda N
FAU - Fujiwara, H
AU  - Fujiwara H
FAU - Hirakawa, S
AU  - Hirakawa S
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Netherlands
TA  - J Cardiol
JT  - Journal of cardiology
JID - 8804703
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cardiac Catheterization
MH  - *Cardiac Output
MH  - Female
MH  - Heart Diseases/*physiopathology
MH  - Heart Rate
MH  - Humans
MH  - Lung Compliance
MH  - Male
MH  - Middle Aged
MH  - Pulmonary Artery/physiology
MH  - *Pulmonary Circulation
MH  - Pulmonary Veins/*physiology
MH  - Vascular Resistance
EDAT- 1996/01/01 00:00
MHDA- 1996/01/01 00:01
CRDT- 1996/01/01 00:00
PHST- 1996/01/01 00:00 [pubmed]
PHST- 1996/01/01 00:01 [medline]
PHST- 1996/01/01 00:00 [entrez]
PST - ppublish
SO  - J Cardiol. 1996 Jan;27(1):21-7.