PMID- 8686138
OWN - NLM
STAT- MEDLINE
DCOM- 19960822
LR  - 20190702
IS  - 0042-4900 (Print)
IS  - 0042-4900 (Linking)
VI  - 138
IP  - 10
DP  - 1996 Mar 9
TI  - Effect of post-coital intrauterine inoculation of porcine reproductive and 
      respiratory syndrome virus on conception in gilts.
PG  - 227-8
AB  - The effect of porcine reproductive and respiratory syndrome virus (PRRSV) on 
      early gestation was investigated by exposing susceptible gilts to the virus 
      shortly after they had been bred naturally. Sixteen gilts were exposed 
      intrauterinely to PRRSV and 23 gilts received a sham inoculum. One day after 
      exposure, and on or about seven, 14, and 30 days after exposure, the gilts were 
      bled and the serum was tested for PRRSV and homologous antibody. The pregnancy 
      status of each gilt was determined on day 30 by ultrasound, and near or at term 
      either by necropsy or by allowing the gilts to farrow naturally. All 16 gilts 
      exposed to PRRSV became infected, as evidenced by the detection of PRRSV in seven 
      of the gilts and homologous antibody in the serum of all of them, whereas all the 
      23 gilts exposed to a sham inoculum remained free of both virus and antibody. Ten 
      of the 16 infected gilts conceived, and 19 of the 23 uninfected gilts conceived, 
      but the difference in conception rate was not statistically significant. 
      Moreover, the mean numbers of live fetuses or pigs per litter of the infected and 
      uninfected gilts were similar (9.7 and 9.3). These results suggest that the 
      intrauterine infection of susceptible pigs with PRRSV at or near the time of 
      conception may have little or no effect on their reproductive performance.
FAU - Lager, K M
AU  - Lager KM
AD  - National Animal Disease Centre, USDA, Ames, Agricultural Research Services, Iowa 
      50010, USA.
FAU - Mengeling, W L
AU  - Mengeling WL
FAU - Brockmeier, S L
AU  - Brockmeier SL
LA  - eng
PT  - Journal Article
PL  - England
TA  - Vet Rec
JT  - The Veterinary record
JID - 0031164
SB  - IM
MH  - Animals
MH  - Arterivirus Infections/*veterinary
MH  - Female
MH  - *Fertilization
MH  - Infertility/veterinary/virology
MH  - Male
MH  - Pregnancy
MH  - Respiratory Tract Infections/*veterinary/virology
MH  - Swine
MH  - Swine Diseases/*virology
EDAT- 1996/03/09 00:00
MHDA- 1996/03/09 00:01
CRDT- 1996/03/09 00:00
PHST- 1996/03/09 00:00 [pubmed]
PHST- 1996/03/09 00:01 [medline]
PHST- 1996/03/09 00:00 [entrez]
AID - 10.1136/vr.138.10.227 [doi]
PST - ppublish
SO  - Vet Rec. 1996 Mar 9;138(10):227-8. doi: 10.1136/vr.138.10.227.